London: Tottenham Hotspur announced on Wednesday that Andros Townsend will be sidelined for around 10 weeks with an ankle ligament problem, effectively ruling him out of the World Cup for England.
"Following further examination and consultation, Andros Townsend is to undergo surgery on his left ankle on Thursday after damaging ligaments during our fixture against Stoke City last Saturday," Tottenham said in a statement on their website.
"The injury is likely to sideline the young winger for up to 10 weeks."
A period of unavailability of 10 weeks would leave Townsend unable to play until the second week in July, by which time England's World Cup campaign in Brazil may already be over.
England manager Roy Hodgson is due to announce his 23-man squad for the tournament on May 12, with England set to open their Group D campaign against Italy in Manaus on June 14.
Townsend, 22, burst onto the scene with Spurs at the start of the season, forcing his way into the England team and playing a key role in the wins over Montenegro and Poland that secured qualification for the World Cup.
The pacy, left-footed wide player has since slipped off the radar, however, starting only five times for Spurs in all competitions since the turn of the year.
England manager Roy Hodgson will reveal his squad for the World Cup on May 12, a day after the Premier League season ends, the Football Association announced on Wednesday.
"This will be an important day for Roy and the players ahead of an exciting summer in Brazil," said Club England managing director Adrian Bevington in a statement.
Hodgson is expected to announce a 23-man squad and name up to seven players on standby in case of injury. The final list of 23 players must be submitted to FIFA on June 2.
England have been drawn to face Italy, Uruguay and Costa Rica in World Cup Group D and will open their campaign with a match against the Italians in the Amazonian city of Manaus on June 14.
Hodgson's side will play Peru in a friendly at Wembley Stadium on May 30 before flying out for a training camp in Miami, where they are scheduled to play further warm-up matches against Ecuador and Honduras.