Ziskin co-founded 'Stand Up To Cancer' (Sutc), a charity to raise research funds, during her health battle, but passed away in June last year.
The organisation has been supported by many Hollywood A-listers including Michael Douglas, Jennifer Aniston and Halle Berry taking part - and now Paltrow, whose father lost his fight with cancer in 2002, has been named as an executive producer for the 2012 fundraiser.
"This broadcast has become a global call-to-action for all those touched by cancer. Like so many people, I know what it's like to lose a family member to this disease, and I'm honoured to stand up in my father's memory," she said in a statement. The telethon will air in the US on September 7.