Real Madrid will be the centre of attraction this weekend when they visit fifth-placed Sevilla in the Spanish Primera Liga with FC Barcelona in Japan contesting the FIFA Club World Cup.
Jose Mourinho's side got their campaign back on track following their defeat to Barca in last weekend's Clasico with a 2-0 triumph against third tier side, Ponferadina midweek, but face a far more difficult test Saturday when they visit Sevilla.
A point will take Madrid back to the top of the table, but Sevilla, who are currently fifth in the table, will make things hard for Mourinho's men, XInhua reported.
Sevilla have become a side that is hard to beat under coach Marcelino, although that defensive toughness has come at the expense of goals as players such as Jesus Navas are carrying out more defensive duties.
The last weekend of games of 2011 kicks off with Sporting Gijon entertaining Espanyol.
Sporting's win away to Rayo Vallecano last week gave the club a morale boost, but they need a win to climb out of the relegation zone.
Mallorca also aim to continue their climb up the table when they face a Getafe side that got some breathing space with a win against Granada last weekend.
Athletic Club Bilbao will hope to return to winning ways after a defeat and two draws in their last three matches, with what should be a comfortable game at home to bottom of the table, Zaragoza.
Bilbao will hope striker Fernando Llorente shakes off a knee injury.
Levante look to continue their incredible season with a visit to Granada, while Osasuna have a chance of closing in on the top six when they entertain Villarreal.
Elsewhere, Real Sociedad can continue to climb up the table away to Racing Santander that has taken four points from the two games since Hector Cuper resigned as first team coach.
Finally third-placed Valencia face sixth placed Malaga.
It will be Valencia's first home game since crashing out of the Champions League and last weekend's defeat to Real Betis. As always, Unai Emery's men will need an early goal in order to calm down the nerves of an always demanding Mestalla crowd.