Born and brought up in Kolkata, Ghosh was the son of documentary filmmaker Sunil Ghosh.
He started his career in advertising. After making hundreds of ads, he went behind the camera in 1994 to direct his first film "Hirer Angti".
The filmmaker, went on to win 12 national awards in various categories. His 2012 directional venture "Chitrangada" won him a special jury award at the 60th National Film Awards ceremony.
For "Arekti Premer Golpo", "Memories In March" and "Chitrangada", he faced the camera to show his acting skills. 49-yr-old Ghosh had won several national and international awards for his work.
Ghosh, who was suffering from pancreatitis, passed away at his residence around 7.30 a.m., his colleague Gautam Ghosh told reporters.
Shocked colleagues and friends gathered at the home of the much awarded filmmaker as news of the death spread.
Rituparno Ghosh receives award winner for Direction of Best Feature Film (English) at the 55th National Film Awards function
The filmmaker, who won 12 national awards in various categories, made movies such as "Chokher Bali", "Unishe April", "Raincoat", "Doshor" and "The Last Lear".
West Bengal Chief Minister Mamata Banerjee condoled the death of renowned film-maker, saying it was a very sad day for Bengal. "We are stunned. In his sudden demise, Bengal has lost an eminent filmmaker. It is a very sad day for us," Banerjee, who visited Ghosh's residence this morning, said.
To enable people to pay their last respect to the director, his body would be kept at Nandan film complex from 3.30 PM to 6 PM, she said. Thereafter, the body would be taken to the Tollygunj Technician studio before cremation, the chief minister said.
The death of renowned film director Rituparno Ghosh is a loss not only to the film industry, but also to creativity, Information and Broadcasting Minister Manish Tewari told reporters.