The 69-year-old has worked with Mortensen in a number of films, and with Pattinson for the first time on "Cosmopolis".
"Viggo and I are kindred souls. We love each other in a very personal way and we keep in touch all the time. Rob is a lot younger but I believe him when he says that he wants to do something else with me," contactmusic.com quoted Cronenberg as saying.
"He (Pattinson) and Viggo would be great in a movie together. They'd get along fantastically and the energy between them would be fantastic," he said.