Bookies have placed the Hollywood hunk at solid 2/1 odds to land the saucy screen role, with Ian Somerhalder snapping at his heels, at 5/1.
According to the Independent, one female has also chancer placed a three-figure sum on Michael Fassbender taking on the role, at odds of 3/1.
Twilight star Robert Pattinson also found his own name at the centre of the 50 Shades of Grey speculation and the gossip was so rife that he claims he had to ring his agent to see if he was actually likely to be offered the role.
His agent reckoned not, so attentions now seem to have turned squarely on Ryan Gosling. As far as the speculation over female role of Anastasia Steele goes, Mila Kunis has been tipped for the role at 3/1, with Scarlett Johansson at 4/1.