He said it is time to settle issues with other countries through negotiations, Geo News reported.
Speaking during a Muslim Hands International Conference, Gilani said: "I strongly believe that better sense will prevail on two sides and we will resolve these issues through dialogue."
Recalling the time when he assumed office in 2008, Pakistan's relations with India, Afghanistan and Iran were not satisfactory, Gilani said he took the initiative in normalising ties with India, in particular.
Giani said he met Indian Prime Minister Manmohan Singh at an international summit and stressed for pursuing the dialogue policy.
He said it was agreed in his several meeting with Manmohan Singh that issues including Kashmir, Sir Creek, Siachen, water and terrorism could be resolved through political will.