Shah Rukh Khan – My Name is Khan (2010)
SRK portrayed Rizwan Khan, a man with Asperger’s Syndrome, with tenderness and honesty—breaking stereotypes while delivering a socially impactful performance.
Ranbir Kapoor – Barfi! (2012)
Ranbir played a mute and hearing-impaired boy who expresses more with his eyes and body than most do with words. A charming and emotionally rich performance.
Priyanka Chopra – Barfi! (2012)
As Jhilmil, a young autistic woman, Priyanka shed her glam avatar and immersed herself in a role filled with innocence and subtle brilliance.
Amitabh Bachchan - Paa (2009)
In the 2009 film Paa, Amitabh Bachchan played the unforgettable role of Auro, a 12-year-old boy suffering from a rare genetic condition called progeria, which causes rapid aging.
Rani Mukerji – Black (2005)
Rani stunned audiences as Michelle McNally, a blind and deaf woman navigating life with fierce determination. Her intense performance remains one of her career bests. Playing Michelle’s mentor and teacher who later battles Alzheimer’s, Big B brought immense dignity and pathos to a role that required both strength and fragility.
Sonam Kapoor - Blind (2022)
The actress plays the character of Gia, a former police officer who loses her eyesight in an accident but refuses to let her disability define her.
Kalki Koechlin – Margarita with a Straw (2014)
Kalki gave a fearless, emotional, and authentic performance as Laila, a young woman with cerebral palsy exploring identity, love, and sexuality.
Hrithik Roshan – Koi… Mil Gaya (2003)
Hrithik played Rohit, a developmentally challenged man who finds friendship and confidence through an alien encounter. His innocence and vulnerability made this role both heartwarming and iconic.
Hrithik Roshan – Guzaarish (2010)
Not once, but Hrithik has several times portrayed such characters with ease. He delivered a performance of a lifetime in Guzaarish', where he essayed the role of a paralyzed magician-turned-radio jockey who files a petition in court seeking permission to end his life. His intense portrayal garnered him widespread acclaim, and boosted his versatility several notches!
Saiyami Kher - Ghoomer (2023)
The actress portrays the role of a cricketer whose life takes drastic turn after she loses her right arm in an accident. Despite the life-altering setback, she refuses to give up on her dream.
Darsheel Safary– Taare Zameen Par (2007)
In a breakthrough role as Ishaan, a young boy with dyslexia, Darsheel brought raw emotion and innocence to the screen. His performance was so natural and moving that it changed how India viewed learning disabilities forever.
Shubhangi Dutt - Tanvi The Great (2025)
The actress is set to play the role of an autistic woman, who aspires to fulfil his father’s dream in the movie. To note, it's her debut movie and so far the glimpse looks promising.
Rajkummar Rao – Srikanth (2024)
Rajkummar Rao played the real-life character of visually impaired industrialist Srikanth Bolla in 'Srikanth'. The actor slipped into the character with extreme excellence, and his distinct portrayal spotlighted his versatility to newer levels.
Anushka Sharma - Zero (2018)
Anushka Sharma played the role of Aafia Yusufzai Bhinder, a brilliant scientist with cerebral palsy. Her portrayal was both emotionally nuanced and inspiring. Starring opposite Shah Rukh Khan, her performance was praised for its authenticity and sensitivity.

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