Bhagyashri Borse was born on May 6, 1999, in Chhatrapati Sambhajinagar  (formerly Aurangabad), in Maharashtra, India. She later lived in Lagos, Nigeria, for seven years during her schooling before moving back to India.

She studied business management (BMS) in Mumbai while also pursuing modelling.

She later got her big break in the Telugu film Mr. Bachchan (2024), directed by Harish Shankar and starring Ravi Teja, for which she received widespread acclaim.

She made her big screen debut by appearing in cameo roles in Hindi cinema with Yaariyan 2 (2023) and Chandu Champion (2024).

Bhagyshri's breakthrough came qith the action thriller Kingdom (2025), where she played a significant rolw alongside Vijay Deverakonda.

Later, she was seen as a lead alongside Ram Pothineni in Andhra King Taluka.

Bhagyashri made her Tamil debut in the film Kaantha, starring opposite Dulquer Salmaan. The film was produced by Rana Daggubati, Prashanth Potluri, Jom Varghese along with Dulquer.

Bhagyashri has also appeared in several television commercials including the ad for Cadbury.

Most recently, she was seen sharing screen with Akhil Akkineni in Lenin.

She has also won several awards over the course of her career, including the SIIMA Award for Best Female Debut – Telugu.

Bhagyashri Borse has a pet dog named Zia. She often shares glimpses of her bond with her pet on her social media, referring to Zia as her "life companion."

The actress recently opened up about her family's financial struggles, saying, "My family, my parents are from a lower-middle-class background. I’ve seen my dad request someone, ‘Please give me a job. I have two daughters."