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Addressing inflammation in diabetics may help treat depression; but outcomes vary: Study

Findings could help develop customised treatment plans for diabetics, who might be doubly vulnerable to depression compared to the general population, the team said

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Image for representational purposes only (Photo Courtesy: iStock)

Image for representational purposes only (Photo Courtesy: iStock)

An analysis has revealed that addressing inflammation in diabetes can help determine success in treating depression in a group of patients. However, there are differences in outcomes between type 1 and type 2 diabetes, researchers said.

While type 2 diabetes is a metabolic condition marked by an inability to manage blood sugar, type 1 diabetes is an autoimmune disorder in which the body's immune system mistakenly attacks and damages insulin-producing cells in the pancreas.

"People with type 2 diabetes and high inflammation levels possibly respond particularly well to a change in depressive cognitions through cognitive behavioural therapy. People with type 1 diabetes and high inflammation levels, on the other hand, could benefit more from anti-inflammatory drug therapies," said author Norbert Hermanns from the Research Institute of the Diabetes Academy Mergentheim (FIDAM), Germany.

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