Sania Mirza's US Open campaign came to a screeching halt with a defeat in the second round of the mixed doubles event while Yuki Bhambri got off to a perfect start in boys' singles, winning his first round match without straining a sinew.

Sania and her Canadian partner Daniel Nestor proved no match for their American opponents Travis Parrott and Carly Gullickson and went down 1-6, 4-6 in under one hour at Flushing Meadows on Sunday.