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US clears trial for wireless brain implant to treat depression
Updated On: 30 April, 2026 08:32 AM IST | Texas | Agencies
Motif Neurotech has received US FDA clearance to begin clinical trials of its wireless brain implant designed to treat depression. The device, which sits in the skull without penetrating brain tissue, delivers targeted electrical stimulation to regulate mood-related circuits

The Motif DOT implant. Pic Courtesy/Rice University
Motif Neurotech has secured clearance from the US Food and Drug Administration to begin its first clinical trial for its brain implant targeting treatment-resistant depression. The Digitally programmable Over-brain Therapeutic (DOT), delivers electrical stimulation to brain circuits linked to depression without penetrating brain tissue as it is placed in the skull.
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