I’m starting to hate my bestie...

I think I am starting to hate my best friend, because of how she has changed over the past few years. We have known each other since school and have been close for most of our lives. Lately, however, it doesn’t feel as if she is the person I grew up with. Much of this has to do with our how circumstances have changed, how our careers are radically different, and how we choose to live our lives. It’s not just that we have nothing in common anymore, it’s also that her choices are at odds with who I am as a person today. I want to end this friendship but part of me feels as if I may regret it as I grow older. What should I do? I am prepared to let her go, but it may be nostalgia that is holding me back.
People change and that is an acceptable part of life. Friendships, like all relationships, can evolve and not always for the better. If you don’t want this person in your life, and believe it is a decision that is in your best interests, you can walk away. Regret may be unavoidable, but there is no way of knowing if your feelings for her will change a few years from now. It is harder to accept people than to reject them though, and you must take that into consideration. You can also choose to distance yourself from her for a while, to gauge how that works for you both. Either way, holding on to someone is always your prerogative, provided you know that it works both ways. Letting her go also frees her from the need to accept you again if you choose to reach out at some point in the future.

What can I do about my ex-boyfriend ghosting me after we ended our relationship? It was an amicable break up and I wanted to stay friends, but he changed his mind.
You may have to accept his decision and move on.