Egyptian national Eman Ahmed Abdulati currently weighs 340 kg

The mystery behind Eman Ahmed Abdulati's massive weight gain has finally been solved. The Egyptian national, who was once touted to be the heaviest woman at 500 kg, has a rare gene defect, LEPR mutation - reportedly making her the first person in the world whose obesity has been attributed to it. The LEPR gene provides instructions for making a protein called the leptin receptor, which is involved in the regulation of body weight. Any mutation in it causes excessive hunger.