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Anthropic’s Claude AI uncovers hidden CRISPR-like system in bacteriophages

Combining an RNA-copying enzyme with a DNA-interacting protein to generate functional guide RNAs, this breakthrough shows how AI can formulate verifiable hypotheses and accelerate molecular biology

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AI GENERATED REPRESENTATION PIC

AI GENERATED REPRESENTATION PIC

Anthropic’s Claude AI discovered a novel CRISPR-like mechanism in bacteriophages — array-associated reverse transcriptase (ART) — by analysing over 200,000 reverse transcriptases.

Combining an RNA-copying enzyme with a DNA-interacting protein to generate functional guide RNAs, this breakthrough shows how AI can formulate verifiable hypotheses and accelerate molecular biology.

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