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New strains of coronavirus dodging RT-PCR tests?

The clinical impact of genetic variants on test sensitivity is influenced by the sequence of the variant, the design of test and the prevalence of the variant in the patient population.

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Family members, wearing PPE kits, wait during cremation of a COVID-19 victim, at the Nigambodh Ghat in New Delhi. Pic/PTI

Family members, wearing PPE kits, wait during cremation of a COVID-19 victim, at the Nigambodh Ghat in New Delhi. Pic/PTI

The rising number of false negative tests for Covid-19, surfacing in the second wave of the pandemic sweeping across India, have become a cause for grave concern. This is being attributed to some new strains of coronavirus that the standard RT-PCR tests are not being able to detect.

There are increasing cases of patients with full-blown symptoms of Covid-19 testing negative. Health experts are of the view that the coronavirus is constantly mutating and some new strains have emerged which may not be detected by the current RT-PCR tests.

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