Andy Murray's comeback was sidetracked on Monday as the three-time Grand Slam champion lost 1-6, 6-1, 4-6 to Lucas Pouille in his opening match at the Cincinnati Masters.

Murray, returning from hip surgery, was unable to get past the French 16th seed, hampering his preparations for the US Open starting on August 27. Murray last played 11 days ago in a Washington third-round match which took him three hours to win and ended at 3 am.