Pusarla V. Sindhu of India reacts after losing a point against Nozomi Okuhara of Japan during their women's singles second round match at the Japan Open Badminton Championships in Tokyo. Pic/AFP

In a major blow to the Indian fans, Rio-Olympic silver-medallist PV Sindhu knocked out of the Japan Open Super Series after going down in straight games against Nozomi Okuhara in the second round here on Thursday.