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First-in-India Breakthrough: Knee Intraosseous Treatment Now at RegenOrthoSport with Dr. Venkatesh Movva

Updated on: 13 September,2025 05:09 PM IST  |  Mumbai
Buzz | sumit.zarchobe@mid-day.com

Discover Knee Intraosseous Therapy at RegenOrthoSport, India’s first non-surgical treatment by Dr. Venkatesh Movva for knee pain & osteoarthritis relief.

First-in-India Breakthrough: Knee Intraosseous Treatment Now at RegenOrthoSport with Dr. Venkatesh Movva

Knee Intraosseous Therapy India

Knee pain is one of the most common orthopedic complaints in India. From athletes to working professionals and seniors, millions of people experience knee discomfort due to osteoarthritis, sports injuries, or wear-and-tear changes. For many, conservative treatments such as painkillers, physiotherapy, or even injections like steroids and PRP bring only temporary relief. On the other end of the spectrum lies knee replacement surgery, which many patients are hesitant to undergo because of risks, costs, and long recovery times.

Until now, the gap between short-term conservative care and major surgery remained unfilled. Introducing Knee Intraosseous (IO) Treatment in India, for the first time at RegenOrthoSport by Dr. Venkatesh Movva, patients now have access to a non-surgical, regenerative alternative that directly targets the root cause of degeneration-inside the bone itself.

What Exactly Is Knee Intraosseous Therapy?


The knee joint is made up of cartilage, ligaments, menisci, and bone. While most treatments focus on cartilage or soft tissues, research has shown that the subchondral bone (the bone layer just beneath the cartilage) plays a crucial role in osteoarthritis progression. Tiny injuries within this bone-called bone marrow lesions (BMLs)-can cause swelling, inflammation, and structural weakness, leading to persistent pain and cartilage breakdown.

Intraosseous Therapy is designed to address this hidden problem. Using image guidance, orthobiologics are injected directly into the subchondral bone, where they stimulate healing, improve bone strength, and reduce inflammation. By treating the foundation of the joint, the therapy not only relieves pain but also protects cartilage and slows down further degeneration.

Think of it like repairing the roots of a tree rather than just trimming its branches-this approach treats the true source of joint damage.

Why Intraosseous Treatment Is a Game-Changer

Most injections such as HCP, stem cell therapy, or steroids work around the joint, reducing surface-level inflammation. While helpful, these treatments often don’t reach the damaged bone beneath. Intraosseous therapy changes the equation-instead of treating symptoms, it rebuilds the joint from the inside out.

Globally, this technique has already gained momentum, especially in the U.S., where long-term studies show significant improvements in pain, joint preservation, and functional mobility. Patients experience:

  • Less inflammation
  • Improved weight-bearing capacity
  • Healthier bone-cartilage interaction

In other words, this isn’t just another knee injection-it’s a paradigm shift in how we treat chronic knee pain.

Who Can Benefit from Intraosseous Treatment?

This therapy is not for everyone, but it is especially beneficial for:

  • Patients with early to moderate osteoarthritis, where joint damage hasn’t reached the advanced stage.
  • Individuals with bone marrow edema (BME) visible on MRI scans.
  • Active adults who want to maintain their lifestyle and delay or avoid knee replacement surgery.

If you’re struggling with ongoing knee pain and your doctor has suggested surgery as the “next step,” this treatment could be the bridge to recovery you’ve been waiting for.

Beyond Knees: Other Joints Where Intraosseous Therapy Can Help

While Knee Intraosseous Therapy is a groundbreaking solution for chronic knee pain and osteoarthritis, its benefits are not limited to the knee joint alone. Since the procedure works by treating bone marrow lesions (BMLs) and subchondral bone degeneration, it can be applied to several other joints affected by similar conditions.

Here are the key areas where IO therapy is proving to be valuable:

  • Hip – Effective for early to moderate hip osteoarthritis, femoral head bone marrow lesions, and early stages of avascular necrosis (AVN). It can also help patients with labral tears combined with bone changes.
  • Shoulder – Useful in glenohumeral osteoarthritis, bone marrow edema of the humeral head or glenoid, rotator cuff–related arthropathy with bone degeneration, and post-traumatic joint pain.
  • Hand & Wrist – Helps in wrist osteoarthritis, chronic wrist pain from subchondral bone injury, thumb base (CMC joint) arthritis, and early avascular necrosis of small wrist bones like the scaphoid or lunate.
  • Foot & Ankle – Beneficial for ankle osteoarthritis, talar dome lesions, bone marrow edema syndrome of the foot, midfoot arthritis with bone changes, and chronic ankle instability linked with bone degeneration.

In essence, any joint affected by bone marrow lesions or subchondral bone injury may respond positively to Intraosseous Therapy. This makes it a versatile, non-surgical option for patients across multiple orthopedic conditions.

Dr. Venkatesh Movva: Bringing U.S. Expertise to Indian Patients

The introduction of Intraosseous therapy in India wouldn’t be possible without the expertise of Dr. Venkatesh Movva. Trained extensively in the United States in the field of interventional orthobiologics, Dr. Movva has pioneered regenerative medicine practices in India through RegenOrthoSport.

By combining U.S.-level protocols with personalized patient care, he ensures that Indian patients receive the same cutting-edge therapies that are transforming lives across the globe. As one of the first doctors in India to perform Intraosseous procedures, Dr. Movva stands at the forefront of this medical innovation.

Benefits of Knee Intraosseous Therapy

Patients undergoing Intraosseous treatment can expect:

  • Pain relief by reducing inflammation in bone marrow lesions
  • Improved function, allowing smoother movement and better joint loading
  • Preservation of the natural joint, avoiding artificial implants
  • Faster recovery compared to surgical interventions
  • A strong possibility of delaying or eliminating the need for knee replacement
  • Minimally invasive, outpatient procedure with minimal downtime

Many patients are able to return to walking, climbing stairs, or even light sports within a few weeks of treatment.

RegenOrthoSport: India’s First Intraosseous Treatment Hub

RegenOrthoSport is proud to be the first center in India to offer this cutting-edge treatment. With state-of-the-art labs, advanced diagnostic imaging, and a team trained in regenerative medicine, we provide patients with access to world-class care without leaving the country.

Our philosophy is simple: heal, don’t replace. By focusing on non-surgical regenerative therapies, we help patients achieve measurable improvements without the risks and long recovery times of surgery.

Real Stories, Real Results

International studies have shown that patients treated with Intraosseous therapy report:

  • Significant reduction in pain within weeks
  • Better walking ability and joint function
  • Long-term improvement in joint health

At RegenOrthoSport, early patients are already experiencing similar outcomes-walking more comfortably, avoiding pain medications, and putting off the need for knee replacement.

Take the First Step Toward Stronger Knees

If chronic knee pain has been holding you back, it’s time to explore this revolutionary alternative.

Book your consultation at RegenOrthoSport with Dr. Venkatesh Movva-India’s first Intraosseous treatment hub.

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