The 37-year-old married Will Kopelman in June and are expecting their first child together later this year.
Barrymore says she wants to have a big family with her new husband.
"I can't wait until I have my children. I love the idea that they don't have to do something that they have no interest in, that they can do something completely opposite if they want to," femalefirstc.co.uk quoted Barrymore as saying.
"I will be so surprised if they don't want to do something involving food or wine or art, but I'll be Ok with it. I just want to build fun, great things for my family," she added.
Spotted: Virat Kohli, Anushka Sharma and other celebs at Mumbai airport
Photos: Salman Khan's 'special friend' Iulia Vantur at a song launch
Photos: Hrithik Roshan, Anushka Sharma, other celebs dazzle at event
In Pictures: Sex scandals involving Indian politicians
Photos: Abhishek Bachchan and Farah Khan at Boman Irani's birthday bash