US Vice President JD Vance is on his way to Pakistan to lead high-stakes negotiations with Iran following a temporary two-week ceasefire. The talks in Islamabad are aimed at securing a long-term agreement and preventing further escalation in the region. Before departing, Vance said the United States is willing to extend an “open hand” if Iran negotiates in good faith, but warned Washington would not be receptive if Tehran tries to “play” the US. President Donald Trump has reportedly provided clear guidelines for the American delegation.