Vir has joined hands with theatre production house Ashvin Gidwani Productions for the new show.
His new performance will focus on a scientific chronology of the struggle between men and women. It will be unveiled to the public Sep 7 at Tata NCPA theatre here.
"After history, it's now time to move onto chemistry. The show is an intellectual comedy based on scientific facts, which will give you a different perspective on your respective other," Vir said in a statement.
"This show is very close to my heart since I've written the script myself after a lot of research and experimentation. We've been patriotic and poignant for two years, now let's have some fun and misbehave," he added.
With theatrical comedies such as "Walking on Broken Das" and "History of India", Vir has taken comedy experiences to another level, making him a noticed standup comedian in the country.
On the Bollywood front, the "Delhi Belly" actor is currently awaiting the release of "Santa Banta", which also stars Neha Dhupia and Boman Irani.