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Australian scientists develop antibody approach to fight antibiotic-resistant bacteria

Australian scientists have developed a novel strategy to combat antibiotic-resistant bacteria by designing antibodies that target a sugar found only on bacterial cells. In laboratory tests, the antibody successfully cleared a normally fatal bacterial infection in mice by binding to pseudaminic acid and triggering the immune system to destroy

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Immune cells (cell boundaries in red and nuclei in blue) engulfing the bacteria seen in green. PIC COURTESY/Peter Doherty Institute

Immune cells (cell boundaries in red and nuclei in blue) engulfing the bacteria seen in green. PIC COURTESY/Peter Doherty Institute

Australian scientists have created a promising new approach for fighting deadly bacteria that no longer respond to antibiotics.

The team designed antibodies that latch onto a sugar found only on bacterial cells, a discovery that could support a new class of immunotherapies.

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