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New study find that every second Indian could be living with high blood sugar

An analysis of four million lab test reports by an online healthcare company in India suggests that every other person could be having high levels of blood sugar. About half of the men and women who tested were found to have had a high blood sugar or 'hyperglycaemia'. Further, over 90 per cent of those having a high blood sugar also showed an abnormality in parameters of liver, lipid, heart or thyroid, the 'Diabetes: The Silent Killer Sweeping Across India' report by PharmEasy said. Findings of the analysis published ahead of World Diabetes Day on November 14 also show a 22 per cent improvement in blood sugar levels among those who retested within six months, highlighting how regular monitoring can be crucial to managing diabetes effectively, the authors said. Diabetes tests conducted by PharmEasy during the period January 2022 to September 2025 were analysed. The authors wrote, "One in two people tested shows high blood sugar levels. 51.9 per cent of men and 45.43 per cent of women who tested had high blood sugar." Looking at how high blood sugar varied across age groups, a sharp increase in reports of high blood glucose was seen among those aged 30 and above. Nearly 60 per cent of the total lab tests -- 64 per cent of men, 54 per cent of women -- also revealed insulin resistance, where the body's cells do not respond to insulin and which is an early sign of one's metabolic risk. One can watch out for insulin resistance through indicators such as dark velvety patches on the back of the neck, armpits or elbows, skin tags on eyelids or elsewhere on the body, or an increase in waist circumference, the authors said. They also found that one in four people with high blood sugar also have a thyroid problem, most commonly an underactive thyroid or 'hypothyroidism'. More than one in three people with hyperglycaemia showed signs of liver problems -- this can happen due to a build-up of fat in the organ, with high blood sugar and insulin resistance as contributing factors, the authors said. Around 90 per cent of the lab reports revealed abnormal cholesterol and fat levels -- often a mix of high 'bad' cholesterol (LDL) and triglycerides, and low 'good' cholesterol (HDL) -- which can significantly raise the risk of heart disease and high blood pressure. Further, nearly half of the reports with high blood sugar showed a dysfunction of the kidney. The authors said that high blood sugar can impair the kidneys in removing waste from the body, while leaking useful proteins in urine. One in three lab test reports showed signs of inflammation that can slowly damage the lining of blood vessels and increase the risk of heart attack and stroke This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

12 November,2025 12:58 PM IST | New Delhi | PTI
Every year, World Pneumonia Day 2025 is observed on November 11 around the globe. Photo Courtesy: File pic

Pneumonia Day: Expert guide to avoiding the pollution-triggered lung infection

Pneumonia, a dangerous lung infection, remains one of the leading causes of illness and comorbidities globally, escalating from a simple cough often due to the compromised air we breathe. Experts emphasise that poor air quality, combined with factors like smoking, significantly raises the risk.  According to the World Health Organization, pneumonia is the single largest infectious cause of death in children worldwide, killing over 7,40,000 children under the age of five in 2019 alone, and almost half of these deaths are associated with air pollution.  On World Pneumonia Day, medical experts delve into the impact of air pollution and smoking on the increased risk of pneumonia and share strategies that can help recognise symptoms. They also recommend adopting corrective lifestyle measures and seeking timely medical care to combat this persistent global health crisis. Air quality, and pneumonia risk in IndiaDr Salil Bendre, director of pulmonology at Nanavati Max Super Speciality Hospital, Mumbai, states, "What often starts with a simple cough, sometimes escalates into a dangerous lung infection, mainly due to the air we breathe, both from the ambient environment and from inside our homes." He explains the mechanism, "Fine particulate matter like PM 2.5 is small enough to travel deep into the lower airways. These particles also carry a mix of toxic chemicals which irritate the airways. They are also linked with acute respiratory infections, such as pneumonia."  He notes that children and women exposed to high concentrations, such as those from solid-fuel-using homes, are particularly at risk. He adds that young children exposed to tobacco smoke and pollution have about two times the risk of pneumonia. Targeted prevention: Strengthening lung resilienceDr Rupali Pattnaik, consultant critical care medicine at Manipal Hospital, Bhubaneswar, emphasises that for individuals living in areas with chronic bad air, prevention must start long before illnesses occur.  She states, "Though masks and air purifiers are useful, the superior defence against airborne pollution is to strengthen our lungs’ ability to resist damage and enhance our body’s natural capacity to filter and respond to soot."  Below, she outlines a few simple strategies for lung defence: Breathing routinesSimple breathing routines, including diaphragmatic and pursed-lip breathing, should be performed daily to assist in respiratory muscle strength and oxygen exchange and help increase the elasticity of your lungs and decrease inflammation of your airway. Additionally, steam inhalation with lukewarm plain water or mild saline can alleviate trapped pollutants in the air passage and provide relief. NutritionAntioxidant-rich superfoods such as citrus, amla, turmeric, berries, green tea, and nuts help to neutralise the free radicals that are produced when pollution is breathed in. Omega-3 fatty acids found in fish, flaxseed, and walnuts are anti-inflammatory and "can prevent the oxidative damage to lung tissue. Adequate hydration is also crucial to keep mucous membranes moist and aid in the natural clearance of inhaled particles. Environmental awareness and indoor qualityIndividuals must schedule outdoor activity when pollution levels are generally at their lowest, such as early in the day and after a rain shower, and stay away during rush hour. Inside, one must maintain good ventilation and incorporate the use of HEPA filters and air-purifying plants like spider plants, aloe vera, or peace lilies to help remove indoor toxins. MonitoringPattnaik advises that those with occupationally related long-term exposures should receive annual lung health evaluations, including spirometry or pulmonary function tests, for early detection of decrements in lung function or airway. Vaccination beyond routine"Vaccination is still the bedrock of pneumonia prevention," Pattnaik asserts, but it must extend beyond routine pneumococcal shots for those with chronic exposure or a smoking history. She lists the key recommended vaccinations:Annual Influenza vaccine: This is strongly recommended because the flu virus can act as a gateway infection, weakening the lungs and facilitating bacterial pneumonia. Covid-19 vaccination and boosters: These remain relevant as SARS-CoV-2 infections may lead to severe lower respiratory tract disease that looks like or leads to pneumonia, particularly in people who already have weakened lungs.Tdap (Tetanus, Diphtheria, and Pertussis): Pertussis (whooping cough) can be especially hard on adults with compromised respiratory systems. RSV Vaccine: Preliminary studies suggest a benefit to older adults and patients with chronic lung disease, as the virus is now increasingly being recognised as an important etiologic agent in adult pneumonia. Pattnaik concludes, “These vaccinations are vital in the long run because they’re also reducing the likelihood of severe disease — and that’s key for people whose respiratory systems are already under stress from their environment." Recognising severity: Five red flags that signal emergencyBendre highlights, “The most common reason for delayed treatment is brushing off the symptoms and not recognising severity early enough. Air pollution and smoking can cause a persistent cough which, in some patients, may progress to pneumonia. In seniors or those with chronic lung disease (like COPD), one might observe confusion, fatigue, or a sudden drop in oxygen levels.” Bendre notes, "Oxygen saturation below 90 per cent and abnormal chest radiographs are strong indicators of the severity of this condition and the need for immediate care." He provides crucial instructions, saying, "It is important to know the red flags, seek immediate care when they appear; and where available, use a pulse oximeter at home to check oxygen levels in high-risk elders or those with COPD." Dr. Bendre lists five warning signs you should go straight to the emergency department:1. Severe unexplained breathlessness or struggling to speak full sentences.2. Oxygen saturation below 90 per cent or a bluish shade on the lips or face.3. Unexplained confusion, drowsiness, or sudden worsening in seniors.4. High fever with chills and low blood pressure.5. Inability to drink or keep fluids down, or signs of dehydration in a child. Treatment effectiveness and complicationsPattnaik says, “A heavy smoking history or long-term exposure to polluted air can make pneumonia more difficult to treat and increases the risk of hospitalisation.” She further explains that pollutants and tobacco smoke destroy the cilia in our airways. This means that once infection takes hold, the lungs are less able to clear bacteria or secretions, which slows recovery.  “Patients with this history are more likely to have underlying chronic conditions like bronchitis or COPD, and reduced lung elasticity, which predisposes them to hypoxia (low oxygen levels). Consequently, they are more likely to be hospitalised for infection, require oxygen therapy, or even sustain critical care," Pattnaik warns.  She advises that antibiotic selection may differ, often consisting of wider-spectrum or multiple antibiotics, as these patients are frequently colonised with resistant bacterial strains or mixed infections. “It is important that oxygen saturation and respiratory rate be closely observed during treatment, with temporary discontinuation of smoking or contamination by pollutants, to allow lung tissue to recover,” she concludes.  Post-pneumonia lung health: RehabilitationPattnaik emphasises that recovery does not end with antibiotics, as the lungs commonly linger in a weakened and inflamed state for weeks. “Without rehabilitation, scarring or chronic bronchitis may take hold," she warns.  Pattnaik outlines the five-step long-term rehabilitation plan:1. Pulmonary rehabilitation: This is a formal program involving breathing exercises, physical conditioning, and education. Patients should start with guided breathing maneuvers such as incentive spirometry and balloon inflation.2. Physical activity: Mild forms of aerobic exercise like walking or swimming will help increase endurance and maximise the peripheral use of oxygen.3. Nutrition: Post-recuperation, foods rich in protein support tissue repair, and antioxidants (Vitamins C and E) counteract oxidative stress. Remember to hydrate as drinking water thins mucus.4. Smoking and environment: A smoking patient must quit. Furthermore, patients must stay away from dust, construction sites, or industrial smoke while recovering and "must wear certified N95 masks if that is not doable.5. Monitoring: Follow-up imaging and pulmonary function test should be performed within 4–6 weeks from recovery to confirm resolution of inflammation. Self-management for lingering symptomsPattnaik recommends evidence-based self-management strategies for home recovery: 1. Fatigue management: Mild physical activity, alternating with proper rest, aides in the recovery of strength without over burdening the lungs.2. Cough management: Do not suppress a productive cough. Instead, use warm fluids, honey with turmeric, or saline gargles to soothe the throat. Running a humidifier or breathing in steam can help relieve irritation and loosen mucus.3. Resuming activity: Exercise should be gradually reintroduced after the patient can walk easily without getting breathless. She mandates a lifelong surveillance for symptoms of poor lung recovery. Practical advice for vulnerable groupsRecognising vulnerable groups is key to targeted prevention and early care. “The most susceptible individuals are children under five years of age, who face the highest risk of contracting pneumonia. Among adults, individuals with COPD are commonly affected due to their long-term exposure to pollution. Furthermore, older age groups witness sharply rising mortality with each passing decade, making focused preventive measures essential for these populations," explains Bendre. He offers practical measures to reduce pneumonia risk across all ages:1. Clean home air: Invest in advanced, vented stoves and better ventilation cut smoke exposure, if in rural areas, cook outdoors or in semi-open spaces. 2. Quit tobacco or exposure to second-hand smoke: Quitting smoking reduces risk of pneumonia in adults. Keep the homes, residential areas, playgrounds, schools and colleges and public areas smoke-free to protect the children. 3. Vaccinations on time: In some cases, measles and pertussis may lead to pneumonia. Routine immunisation can reduce the episodes. 4. Supporting nutrition and immunity of children: Exclusive breastfeeding for six months, sufficient complementary feeding, and supplementation as recommended by the paediatrician can reduce respiratory infections.

12 November,2025 12:57 PM IST | Mumbai | Maitrai Agarwal
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AI could revolutionise healthcare delivery: Dr Naresh Trehan

The 22nd CII Annual Health Summit was held on Tuesday, with the theme 'Adding Life to Years in the Age of Artificial Intelligence,' in New Delhi. While speaking at the Health Summit, Dr Naresh Trehan, Chairman, CII Steering Group on Health & Healthcare Council and CMD, Medanta - The Medicity, said, "Providing quality healthcare to all citizens is a key priority for Governments worldwide and particularly for India, with its population of 1.4 billion. India has made significant progress through various Government initiatives, strong public-private partnerships, and a vibrant private healthcare sector." "However, with expanding healthcare needs driven by rising rates of obesity, cancer, and other chronic conditions, new solutions are essential. AI holds immense potential to transform healthcare delivery by expanding access, enhancing expertise, reducing costs, and improving overall efficiency," he added. Suneeta Reddy, Managing Director, Apollo Hospitals, said, "India has witnessed remarkable improvements in key healthcare indicators, including reductions in infant and maternal mortality rates, the availability of affordable treatment, and growing medical tourism, with patients arriving from over 140 countries." "The creation of more than 79 crore ABHA IDs underscores the country's progress in building a robust digital health ecosystem. With over 250 million health data points and a strong foundation in intellectual property and digital technologies, Artificial Intelligence (AI) offers immense potential to further scale and strengthen India's healthcare system. As non-communicable diseases continue to rise, it is imperative for India to harness the power of AI for early detection, prevention, and better health outcomes," she added. Dr Kenji Shibuya, Chief Executive Officer, Medical Excellence, Japan, said, "Collaboration between India and Japan can play a pivotal role in shaping a broader healthcare agenda for the future. Ayurveda, one of India's enduring strengths, offers a holistic approach to wellness, and integrating AI into this traditional system can greatly enhance its effectiveness in addressing a wide range of health conditions, including chronic inflammation and lifestyle-related diseases. Japan's well-established expertise in preventive healthcare complements India's capabilities, creating a powerful synergy. This partnership stands as a model of robust South-South cooperation, demonstrating how shared knowledge and innovation can advance global health outcomes." The theme for the Summit, 'Adding Life to Years in the Age of Artificial Intelligence', is both visionary and urgent, as mentioned by Amita Sarkar, Deputy Director General, CII. A tripartite MOU between CII, MEJ, and ERIA was exchanged, marking a new chapter of collaboration in healthcare technology, policy research, and capacity building across the Indo-Pacific. "This MoU underscores a shared commitment to fostering an inclusive, resilient, and sustainable healthcare ecosystem between India and Japan", said Dr Takayuki Yamanaka, Chief Operation Officer, Economic Research Institute for ASEAN and East Asia (ERIA). "As India advances toward the vision of Viksit Bharat, reimagining healthcare through the lens of AI is both an opportunity and a necessity", highlighted Dr Shubnum Singh, Principal Advisor, Healthcare, CII. "It captures the promise of technology to not just extend life, but to improve the quality and dignity of those additional years. AI and digital tools are redefining diagnostics, research, and patient engagement, but the true test lies in how intelligently and inclusively we apply them to strengthen our health systems and empower our people," she added. This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

12 November,2025 10:14 AM IST | New Delhi | ANI
Every year, World Pneumonia Day is observed on November 12 around the world. Image for representational purpose only. Photo Courtesy: istock

Mid-Day Premium Stop feeding pigeons! Mumbai docs say the bird's dropping can cause pneumonia

As Mumbai slowly settles into its winter, doctors warn about the rise in pneumonia cases, but more than that, they highlight the possibility of getting it through pigeons. Incidentally, World Pneumonia Day is observed on November 12 every year around the world to raise awareness about the need for prevention and treatment of the lung infection. Firstly, what is pneumonia? Dr. Sulaiman Ladhani, pulmonologist at Wockhardt Hospitals in Mumbai Central, explains, "Pneumonia is an infection of the lungs caused by bacteria, viruses, fungi, or other microorganisms. The common types are bacterial, viral, and fungal pneumonia."  While pneumonia is usually found to be on the rise during the winter months, feeding pigeons is another reason that Mumbai doctors highlight as the reason for the cause of hypersensitive pneumonia. On more than one occasion, Thane Municipal Corporation has put up posters in the last few years warning people against feeding pigeons.  With the winter season almost here, mid-day.com spoke to Dr Revathy Kodakkal, consultant - Respiratory & Sleep Medicine, Holy Family Hospital in Bandra and Dr Ladhani to know more about the infection. They not only highlighted the causes but also effects and treatment of the respiratory disease. The Mumbai experts also warn about how people can get pneumonia because of pigeons. What are the causes of pneumonia, and what are the different types? Kodakkal: Bacterial pneumonia, commonly caused by Streptococcus pneumoniae, is prevalent, while viral pneumonia often results from influenza and respiratory syncytial virus (RSV). Fungal pneumonia is less common, mostly affecting individuals with weakened immune systems.  Which is the season known to see a spike in pneumonia cases? Kodakkal: Winter months typically see a spike in pneumonia cases due to increased indoor gatherings and a higher incidence of respiratory infections.  What are the signs and symptoms to recognise pneumonia? Can the symptoms be confused with any other disease? Kodakkal: The symptoms of pneumonia include high fever, chills, cough with phlegm, difficulty breathing, and chest pain. Since these symptoms can resemble other respiratory infections, like bronchitis or the flu, which sometimes delays diagnosis, fatigue and muscle pain can also add to the confusion with viral infections.  Ladhani: The symptoms can sometimes resemble the flu or bronchitis, which can delay diagnosis. A medical evaluation, often including a chest X-ray, helps confirm pneumonia.  Which age group is most affected by pneumonia? Does it also affect one gender more than another? Kodakkal: Pneumonia most commonly affects young children under five and older adults over 65, especially those with underlying health conditions. It does not appear to impact one gender more than the other, though lifestyle factors may increase susceptibility.  Ladhani: Elderly individuals often face higher risks due to weaker immune systems. While it can affect all genders, men, especially older men with preexisting conditions, may experience more severe cases.  What are the short-term and long-term effects of pneumonia? Kodakkal: Short-term effects include fever, cough, and respiratory distress, which can generally resolve with treatment. Long-term complications are more common in elderly patients and those with weakened immune systems.  Ladhani: Long-term effects can include lung scarring and reduced lung function, especially in severe or repeated cases. People with chronic lung conditions or weakened immune systems might face recurrent pneumonia.  Which section of the population is most vulnerable to pneumonia? Ladhani: Vulnerable groups include young children, elderly individuals, those with chronic illnesses (like asthma, diabetes, or heart disease), smokers, and those with weakened immune systems, such as people with HIV or undergoing chemotherapy.  Do people take pneumonia for granted? Kodakkal: Yes, people often underestimate pneumonia, mistaking it for a common cold or flu. This can lead to delayed treatment, worsening the infection, and increasing the risk of severe complications. Pneumonia can be life-threatening if left untreated, particularly in high-risk groups, so it’s crucial to take symptoms seriously.  What are the treatment options for pneumonia? Kodakkal: Treatment depends on the cause: antibiotics for bacterial pneumonia, antiviral medications for certain viral pneumonias, and antifungal treatments for fungal types.  Should people self-medicate or when should they visit the doctor? Kodakkal: Self-medication is not recommended, as inappropriate drugs can worsen the condition.  Ladhani: A doctor’s visit is crucial if symptoms like high fever, chest pain, or persistent cough occur.  There have been reports in the last year about pneumonia cases due to pigeons in Mumbai. What is the connection between the two? Kodakkal: Pigeon droppings contain fungi and bacteria, like Chlamydia psittaci, which can cause respiratory infections, including a type known as "bird fancier’s lung” or hypersensitivity pneumonitis. Inhaling these microorganisms can lead to lung inflammation and even pneumonia in susceptible individuals.  Ladhani: The respiratory condition related to pigeon droppings is hypersensitivity pneumonitis, which is not the same as bacterial or viral pneumonia. If left untreated, hypersensitivity pneumonitis can lead to irreversible lung scarring and drying. This issue has been ongoing for quite some time, especially in areas where people regularly feed pigeons and spend time among them. Being in close quarters with pigeons, particularly in areas with a high pigeon population, is a common cause of this condition.  Has Mumbai seen a spike in cases of pneumonia due to pigeons? Ladhani: Yes, Mumbai has seen increased respiratory infections linked to pigeons in certain areas.  What are the preventive measures? Kodakkal: Follow these steps: 1. Don't feed pigeons and discourage others from doing so too. 2. Place pigeon nets on balconies and windows where they visit. 3. Avoid keeping other birds as pets. 4. Visit your pulmonologist for persistent cough or breathlessness.  Ladhani: Preventive measures also include wearing masks to reduce exposure to pigeon droppings and avoiding areas with large pigeon populations.  What are the different kinds of foods that people can eat to prevent pneumonia and after suffering from pneumonia? Kodakkal: For prevention, a diet rich in vitamins A, C, and E along with foods high in antioxidants—like citrus fruits, berries, and leafy greens—can support immune health. After a pneumonia diagnosis, focus on hydration and nutrient-dense foods like soups, broths, and soft fruits to aid recovery. Foods with antiinflammatory properties, such as ginger and turmeric, can also be beneficial.  Ladhani: A diet rich in protein, adequate hydration, and rest are important for recovery from pneumonia. Foods that support immune health include those high in protein, such as lean meats, legumes, and dairy. Staying hydrated is also crucial, as it aids in overall respiratory health and recovery.

11 November,2025 04:25 PM IST | Mumbai | Nascimento Pinto
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Nagaland University researchers unlock medicinal secrets of rare Meghalaya plant

A research team from Nagaland University, the only Central university in the state, has partnered with an Assam-based private varsity to carry out the first comprehensive scientific study on Goniothalamussimonsii, an endangered and endemic medicinal plant found in the forests of Meghalaya. Long used by indigenous communities to treat gastrointestinal complications, throat irritation, typhoid fever, and malaria, this plant had never before been studied for its scientific or pharmacological potential. Nagaland University officials said that the study provides scientific validation for the plant’s traditional use and reveals that G. simonsii is a rich source of bioactive phytochemicals with potent antioxidant, antimicrobial, and anticancer activities. Using advanced analytical tools and computational modelling, the team demonstrated how natural compounds from this species interact with cancer-related proteins, offering valuable leads for the development of new, nature-based therapeutic drugs. The Research was led by Dr Mayur Mausoom Phukan, faculty, Nagaland University, with his student Samson Rosly Sangma. The findings were published in October 2025 in a reputable journal. The paper was co-authored by Sangma, research scholar; Dr Phukan, Assistant Professor, Department of Forestry; Dr Pranay Punj Pankaj, Associate Professor, Department of Zoology, Vahshi Chongloi, Research Scholar of the Nagaland University and Dr Dhrubajyoti Gogoi, Assistant Professor of the Assam-based private varsity. Speaking about this research, Prof. Jagadish K Patnaik, Vice Chancellor, Nagaland University, said, “Nagaland University, in collaboration with Assam’s private University, have undertaken the first comprehensive scientific study on Goniothalamussimonsii, an endangered and endemic medicinal plant native to the forests of Meghalaya.” “Through this study, our researchers are not only contributing to the conservation and understanding of a rare plant species but are also helping to bridge the gap between traditional knowledge and modern science,” the VC said. Commending the research team for their dedication and innovative approach, Prof. Patnaik said that he is confident that this work will open new pathways for sustainable utilisation of our rich biodiversity. “Nagaland University remains committed to promoting excellence in research and fostering collaborations that contribute to the scientific, cultural, and ecological advancement of the region,” he added. Elaborating on this research, Dr Phukan said: “This study bridges traditional knowledge with modern science at a crucial time when antibiotic resistance, chronic illnesses, and the side effects of synthetic drugs continue to strain healthcare systems.” “Our findings reaffirm that India’s rich biodiversity holds untapped potential for modern drug discovery. Goniothalamussimonsii not only offers pharmacological promise but also underscores the urgent need to conserve such endangered species,” he stated. Highlighting the unique aspects of this research, Sangma said, “What makes this research particularly significant is that Goniothalamussimonsii is an exceptionally rare species, with its population declining alarmingly and now confined to only a few natural habitats.” He said that this decline is largely attributed to the limited awareness of its medicinal importance among local communities. Listed as ‘Endangered’ by the International Union for Conservation of Nature (IUCN), this remarkable plant now faces an urgent need for focused conservation efforts. “By generating robust scientific data, we hope that our work will encourage conservation and cultivation initiatives for this rare plant, ensuring its sustainable use and protection in the wild,” Sangma added. Beyond its immediate medicinal implications, this study represents a model for how traditional ethnomedicinal knowledge can be combined with modern biotechnological and computational methods to unlock new possibilities for drug discovery. It also reflects India’s growing emphasis on using indigenous biodiversity as a foundation for affordable, accessible healthcare innovations. Moving forward, the researchers plan to conduct in vivo and clinical studies to validate these findings further and explore the plant’s potential as a component of future phytopharmaceutical formulations. This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever.

11 November,2025 03:31 PM IST | Kohima | IANS
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Australia leads first trial of gene editing therapy to halve bad cholesterol

Researchers in Australia have led a first-in-human trial for a breakthrough gene-editing therapy that halves bad cholesterol and triglycerides in people with difficult-to-treat lipid disorders.  The trial tested CTX310, a one-time CRISPR-Cas9 gene-editing therapy that uses fat-based particles to carry CRISPR editing tools into the liver, switching off the ANGPTL3 gene. Turning off this gene lowers LDL (bad) cholesterol and triglycerides, two blood fats linked to heart disease, according to a statement released Monday by Australia's Monash University. The Victorian Heart Hospital, operated by Monash Health in partnership with Monash University, treated three of 15 patients aged 18-75 years with difficult-to-treat lipid disorders in phase 1 of the global trial conducted across Australia, New Zealand, and Britain, the statement said, Xinhua news agency reported. At the highest dose, a single-course treatment with CTX310 resulted in a mean reduction of LDL cholesterol by 50 per cent and triglycerides by 55 per cent, remaining low for at least 60 days after two weeks of treatment, it said, adding LDL cholesterol and triglycerides were reduced by nearly 60 per cent among all participants with various doses, with only mild, short-term side effects reported. Importantly, CTX310 is the first therapy to achieve large reductions in both LDL cholesterol and triglycerides at the same time, marking a potential breakthrough for people with mixed lipid disorders who have elevations in both, according to the trial published in the New England Journal of Medicine. "The possibility of a single-course treatment with lasting effects could be a major step in how we prevent heart disease," said Stephen Nicholls, Director of the Victorian Heart Hospital, and study lead investigator. "It makes treatment easier, reduces ongoing costs, relieves pressure on the health system, all while improving a person's quality of life," Nicholls said, emphasising plans to focus on larger and more diverse patient populations in future trials of CTX310.

11 November,2025 03:21 PM IST | Melbourne
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New study suggests link between chronic fatigue and irregular breathing

Researchers have found that people with chronic fatigue syndrome tend to experience shortness of breath, which offers a target for treatment and may bring relief from symptoms. Chronic fatigue syndrome is marked by exhaustion that persists despite rest and cognitive problems, including brain fog and difficulty concentrating. The researchers from the US' Icahn School of Medicine at Mount Sinai monitored 57 patients diagnosed with chronic fatigue syndrome while performing physical activity. Results published in the journal Frontiers in Medicine show dysfunctional breathing can look like a deep sigh while breathing ordinarily, overly rapid breathing or shallow breathing so that lungs are never properly breathing. A loss in coordination between chest and abdomen could also prevent the varied muscles that help one breathe from working together, they said. "While we know the symptoms generated by hyperventilation, we remain unsure what symptoms may be worse with dysfunctional breathing," author Dr Donna Mancini from the Icahn School of Medicine said. "But we are sure patients can have dysfunctional breathing without being aware of it. Dysfunctional breathing can occur in a resting state," Dr Mancini said. The authors wrote, "Dysfunctional breathing and hyperventilation are common in patients with ME/CFS (chronic fatigue syndrome) and could present a new therapeutic target for these patients." Heart rate and blood pressure of the participants, which also included 25 healthy ones, were measured along with oxygen saturation of blood, while doing cardiopulmonary exercises over two days. How fast, hard or effectively the participants breathed to get oxygen and patterns in breathing were observed to differentiate hyperventilation and dysfunctional breathing, the researchers said. While participants having chronic fatigue were seen to take in the same amount of oxygen as the healthy ones, 71 per cent were seen to experience breathing problems -- either hyperventilation, dysfunctional breathing, or both. Both dysfunctional breathing and hyperventilation can cause symptoms similar to chronic fatigue, such as dizziness, difficulty focussing, a shortness of breath and exhaustion, the researchers said. Combining the two -- nine patients of chronic fatigue showed dysfunctional breathing and hyperventilation. It can also cause people to experience heart palpitations, chest pain, fatigue, and anxiety, they said. The team suggested that breathing problems could worsen or even directly contribute to post-exertional malaise, in which symptoms of chronic fatigue syndrome get worse following mental or physical exercise. This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

11 November,2025 02:23 PM IST | New Delhi | PTI
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Huge spike in number of cases: Docs warn of health issues due to air pollution

Medical specialists have warned residents of Delhi-NCR about a severe health crisis triggered by the high air pollution in the region. Dr Arvind Kumar, Thoracic (Chest) Surgeon & Lung Health Specialist, Medanta Hospital, said that hospitals are seeing a spike in cases related to effect of pollution The NCR Region faces poor air quality with the Air Quality Index (AQI) recorded at 345 at 8 am. on Monday, placing the national capital firmly in the 'very poor' category. While talking to ANI, Dr Arvind Kumar described how hospitals are overwhelmed with respiratory cases, especially among children, due to air pollution. It includes symptoms like cough, cold, fever and difficulty breathing. "There are patients all around. Everywhere, children are being brought to hospitals coughing, sneezing, having a runny nose, breathing fast, and having a fever. We have patients who are coming back with a cough or pneumonia. There is a huge spike in the number of chest cases. It's all the doctors across the city," said Dr Arvind Kumar. While addressing the result of growing concerns among the national capital's population due to air pollution, the Chest Surgeon said that people have resorted to the usage of Nebulisers, which help patients inhale medicine directly into their lungs. "The most common thing being used today is the nebuliser. Many of my friends have bought the machine. It is actually wrong because self-administration of medicine can be harmful. Once you are breathing in air with AQI of 700, there is no way that you can avoid these diseases," said Arvind Kumar. The Thoracic (Chest) Surgeon & Lung Health Specialist of Medanta Hospital advises people to "stay indoors" and avoid going to "crowded areas" to keep themselves safe from the high air pollution. "Stay indoors as much as you can. Avoid going to crowded areas. Take medicines regularly. Keep yourself well hydrated. Avoid fatty foods. If you develop redness or itchiness in the eyes, you can put ice-cold water," added Dr Arvind Kumar. Meanwhile, the air quality in the national capital plunged into the 'severe' category on Sunday, with the overall Air Quality Index (AQI) recorded at 391 at 7 am, according to data from the Central Pollution Control Board (CPCB). Several parts of the city registered alarming pollution levels with AQI readings crossing the 400-mark. As per CPCB data, Anand Vihar recorded an AQI of 412, Alipur reported 415, and Bawana registered the highest level at 436. Chandni Chowk recorded an AQI of 409, while RK Puram and Patparganj logged 422 and 425, respectively. Sonia Vihar also recorded a 'severe' AQI of 415, indicating hazardous air conditions across the city. Since Diwali, the Air Quality Index (AQI) in Delhi and the National Capital Region (NCR) has been reeling under the 'poor' and 'very poor' categories in several areas, even as Stage 2 of the Graded Response Action Plan (GRAP) remains in effect. The New Delhi Municipal Council (NDMC) has already announced the doubling of parking fees across the national capital after the Graded Response Action Plan (GRAP) Stage II was invoked due to deteriorating air quality. According to CPCB, an AQI between 0 and 50 is considered 'good', 51-100 'satisfactory', 101-200 'moderate', 201-300 'poor', 301-400 'very poor', and 401-500 'severe'. This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever.

10 November,2025 02:38 PM IST | Gurugram (Haryana) | ANI
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Are cheeseburgers healthy?

Cheeseburgers are extremely mouthwatering and that is what makes them tempt each and every one of us who loves cheese or burgers. While the classic cheeseburger has delicious ingredients that include two buns loaded with a ground beef patty, melted cheese, juicy tomatoes, lettuce, and onions, the vegetarian versions, have also become popular over time. However, Mumbai doctors say you may have to reconsider everything you love about the delicious version of the burger, for the sake of your health.  Interestingly, the glorious burger enjoys many different days to celebrate the creation including International Burger Day May 28, National Burger Day on August 21, and most recently National Cheeseburger Day on September 18. While there are many different types, the latter is easily the most desirable, especially because of all the cheese that is added to the dish.  Are cheeseburgers healthy? At a time when the focus on health is more than ever before, and ahead of the holiday season, which is usually associated with binge-eating, health experts serve a reminder. Suvarna Sawant, chief dietician and HoD, Clinical Nutrition and Dietetics, Nanavati Max Super Speciality Hospital in Mumbai shares, “Cheeseburgers, at least the way they are served traditionally, are not healthy. They are rich in calories, fats and low in fibre. Especially with the western influenced foods available today, if served with original ingredients such as refined-flour bun, high-fat patty, cheese, and salty sauces, such fast foods will only increase the risk of chronic diseases.” Fauziya Ansari, who is the dietitcian at Apollo Spectra Hospital in Tardeo, says cheeseburgers are loved by many, especially children but should be enjoyed occasionally. She explains, “Remember that eating them frequently can take a toll on the heart. Cheeseburgers are high in saturated fats, cholesterol, and sodium, which can increase the risk of heart disease and weight gain. So, don’t rely on cheeseburgers or other junk items that can impact the overall well-being.” In fact, she recommends enjoying them every eight to nine months and avoided as much as possible because they are loaded with saturated fats, calories, and sodium. If you are still not convinced, the city-based dietitian highlights the nutrition content of each cheeseburger. “A cheeseburger contains around 300–600 calories, with 15–30 grams of fat, 20–40 grams of carbohydrates, and 15–30 grams of protein. It is jam-packed with sodium and has a lower number of vitamins and minerals, depending on the toppings used,” she shares. Easy tips to make cheeseburgers healthyAvoiding cheeseburgers is literally the best option to stay away from its effects on one’s health, according to both the dieticians, by simply controlling your cravings and choosing healthy options such as fresh fruits. However, if you still want your fix of cheeseburgers, then they suggest using some quick alternatives. Ansari further adds, “There is a common myth that the cheeseburger must be heavily spiced or greasy to suit the Indian palate. However, it is not true at all. Fresh ingredients and moderate seasoning can make them tasty and nutritious.” So, how can cheeseburgers be made healthier? She says, “Using millet veggie burger, sweet potato burger, paneer, or a chana burger can be a good option. Focus on grilled or baked cooking methods, use whole grain buns, and add a lot of fresh vegetables and healthy fats instead of those calorie-laden sauces and cheese. Use roasted or steamed veggies as the filling. Use lettuce instead of burger buns to wrap your burger and all the fixings.” Using healthy and indigenous ingredients, especially for children, explains Sawant can help a lot because it can keep the appearance of the burger intact but use local seasonal produce. She suggests, “The buns can be made of whole-wheat or multigrain. Replacing polished or refined cereals with whole grains introduces fibre in the burger. Secondly, the patties need to be healthier by grilling the chicken tikka on tawa with limited oil or for vegetarians, you can make the patties with paneer, tofu, rajma-galouti, chana-masala, or mixed-dal. You can add finely chopped seasonal vegetables like carrot, beetroot, spinach for fibre and micronutrients in them. Use fresh vegetables like onion, tomato, lettuce to be added with the patty. For protein intake, you can add pulses.”Lastly, the city-based dietitian says skip sugary sauces and add chutney and dip made from coriander-mint-lemon, hung-curd dip, or tomato-onion instead.

09 November,2025 06:43 PM IST | Mumbai | Nascimento Pinto
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"We discovered the secret of life": Nobel Prize winner James Watson passes away

"We have discovered the secret of life," said American scientist James Watson in 1962, along with Maurice Wilkins and Francis Crick, as the trio shared the Physiology and Medicine Nobel Prize for the DNA's double helix structure discovery.  Famous geneticist Watson, who died at 97 as confirmed by Cold Spring Harbor Laboratory in the US -- where he worked and researched for decades -- was associated with one of the greatest breakthroughs of the 20th century. Although DNA was discovered in 1869, it took scientists until 1943 to discover that it made up the genetic material in cells. To date, the structure of DNA remains a mystery. Watson died on Thursday, November 6 (US time) after a brief illness, according to a statement from his former employer. “I think early on, I wanted to do something important with my life. I still want to think about science and really nothing else,” Watson was quoted as saying in CNN in 2013. Being driven by the desire to find the truth, that’s really my legacy. The truth, sometimes you don’t find it and it’s complicated, but what you always have is that if you can start with the truth, it’s helpful, he added. Born in the US state of Chicago in April 1928, he won a scholarship to study at the University of Chicago at age 15. To pursue his research into DNA structures, he went to Cambridge University in England, where he met Crick. Together, they began constructing large-scale models of possible structures. As per reports, Watson took over the Cold Spring Harbor Laboratory in New York State in 1968. He is credited with turning it into one of the world's foremost scientific research institutions. However, his extra-ordinary work was marred owing to his “racist and homophobic remarks” against various groups of people, claiming they had genetic differences. The remarks led to him losing some of his honorary titles. Watson also made headlines when he sold his Nobel Prize in 2014 for $4.76 million at auction. Watson told CNN in 2013: “DNA was my only gold rush. I regarded DNA as worth a gold rush.” This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever.

09 November,2025 01:33 PM IST | New Delhi | IANS
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India ranks second globally in chronic kidney disease cases, says study

India had the second-highest number of people with chronic kidney disease in 2023 at 138 million, following China at 152 million, according to a global study published in The Lancet journal. The condition was the ninth-leading cause of death and claimed nearly 15 lakh lives globally the same year, researchers led by those at the Institute for Health Metrics and Evaluation (IHME) at the University of Washington and other institutes in the US and UK found. The highest prevalence was seen in North Africa and the Middle East at 18 per cent each, nearly 16 per cent in South Asia and over 15 per cent in each of Sub-Saharan Africa and Latin America and the Caribbean. Chronic kidney disease is a major contributor to heart disease and accounted for almost 12 per cent of cardiovascular deaths around the world in 2023. It ranked as the seventh leading cause for heart-related mortality, ahead of diabetes and obesity, the team said. Fourteen risk factors for chronic kidney disease were detailed in the study, with diabetes, high blood pressure, and obesity driving the highest loss in healthy living. "Chronic kidney disease is both a major risk factor for other leading causes of health loss and a significant disease burden in its own right. Yet, it continues to receive far less policy attention than other non-communicable diseases, even as its impact grows fastest in regions already facing the greatest health inequities," senior author Theo Vos, professor emeritus at IHME, said. The researchers analysed data from the Global Burden of Disease (GBD) 2023 study, tracking trends in disease, injuries and health risk factors across 204 countries and territories from 1990 through 2023. The IHME coordinates the GBD study. Dietary factors, such as a low intake of fruits and vegetables and a high consumption of sodium, also made substantial contributions towards one's risk of chronic kidney disease, they said. The authors said that in 2023, most people with chronic kidney disease were in the early stages, highlighting the importance of screening programmes and strategies addressing disease risk. The measures can help reduce heart-related deaths due to kidney disease and delay one's requirement of replacement therapies, usually seen in advanced stages of the disease, the team said. Because access to kidney replacement therapies, including dialysis and transplantation, remains limited and uneven worldwide, a greater emphasis is needed on preventing disease progression and ensuring equitable care, they added. Improving access to diagnosis and affordable care, tackling key risk factors, and investing in strategies that prevent the disease from advancing will be essential to address the growing burden of chronic kidney disease on patients, families, and health systems worldwide, the researchers said. This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

08 November,2025 09:54 AM IST | New Delhi | PTI
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