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High blood pressure damages healthy kidneys: Study

A new research published in 'Kidney International' by a team of scientists led by Enno Klussmann of the Max Delbruck Centre and the DZHK, has found that unless you happen to have PDE3A gene mutation, high blood pressure eventually damages the kidneys. It means that the mutation that causes severe hypertension also shields the kidneys from harm."This mutation causes extremely high blood pressure, but the kidneys still work normally even after years of having the condition," said Dr Enno Klussmann, head of the Anchored Signalling Lab in Berlin. He and his team at the Max Delbruck Center and at the German Center for Cardiovascular Research (DZHK), have now published their results in "Kidney International." Getting to the heart of the matterLast year, researchers discovered that the gene mutation responsible for causing extremely high blood pressure and short fingers (hypertension and brachydactyly, or HTNB) also protects the heart from hypertension-induced damage. Only the brain remains vulnerable: "Without treatment, patients with HTNB - a genetic disease that occurs in just 10 to 20 families globally - tend to die relatively young from a stroke," said Klussmann. "So even children have to take antihypertensive drugs to control their blood pressure." But with medication, it can be hard to bring the blood pressure down to an average level. After discovering that the mutated PDE3A gene protected the heart, Klussmann and his team began investigating a female patient's kidneys in Germany and two HTNB rat models. The patient received treatment from Dr Stephan Walter at MVZ Nierenzentrum Limburg, a specialist kidney centre. The rat models had the same PDE3A mutation as human patients (PDE3A stands for the enzyme phosphodiesterase 3A) and were developed by researchers led by professor Michael Bader. Bader heads the Molecular Biology of Peptide Hormones Lab at the Max Delbruck Center. He and Walter are also authors of the latest study. All parameters in the normal rangeIn patients with severe HTNB, the PDE3A gene was mutated in two places and these mutations cause the encoded enzyme to become hyperactive. "We don't yet fully understand why that happens, or how the mutation damages the vessels and the brain while protecting the heart and the kidneys," said Klussmann. He and his team could, however, show that the kidneys of the Limburg patient are working perfectly normally. "We found that the secretion of the renin - a hormone-like enzyme that's produced in the kidneys and heavily involved in controlling blood pressure - is actually suppressed in her case," said Anastasiia Sholokh, a researcher in Klussmann's team and lead author of the study. "Her aldosterone levels are normal." Aldosterone is a hormone made in the adrenal glands. Like renin, it can cause blood pressure to rise. "Conventional parameters of kidney function like glomerular filtration rate and albumin levels in the blood and urine also indicate that her kidneys are healthy," said Sholokh. Imitating the mutation's effectsThe kidney tissue in the HTNB rats also showed no signs of inflammation or fibrosis (increased production of connective tissue that causes organs to harden). The transcriptome, which shows what genes were active, was also unchanged in the rats' kidneys. "What we did find is reduced expression of the protein amphiregulin in certain regions of the organ," said Sholokh. "Since high levels of amphiregulin are likely to damage the kidneys, the suppressed production probably helps to protect them." "We showed that hypertension doesn't always automatically lead to kidney damage," said Klussmann, summing up. "Now we want to examine the protective effect of the mutated PDE3A gene and see if we can mimic it with appropriate therapeutic agents." This could eventually help patients with hypertension avoid developing chronic kidney disease.Also Read: Is mental health support a key element of inclusive work culture? This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/ reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

03 June,2023 04:42 PM IST | Berlin | ANI
Image for representational purpose only. Photo Courtesy: istock

Male babies talk more in first year than female babies: Study

A new study published in iScience has found that male infants talk more than female infants in the first year. It is known that young babies emit a lot of squeals, vowel-like noises, growls, and brief word-like sounds. These 'protophones' or predecessors to speech, are gradually replaced by early words and, eventually, entire phrases and sentences. While some newborns are inherently more "talkative" than others, researchers have found that there are disparities in the amount of noises made by males and females. While the research confirms earlier findings from a much smaller study by the same team, they still come as a surprise. That's because there's a common and long-held belief that females have a reliable advantage over males in language. They also have interesting implications for the evolutionary foundations of language, the researchers say. "Females are believed widely to have a small but discernible advantage over males in language," says Dr Kimbrough Oller of the University of Memphis, Tennessee. "But in the first year, males have proven to produce more speech-like vocalisation than females." Male infants' apparent early advantage in language development doesn't last however. "While boys showed higher rates of vocalisation in the first year, the girls caught up and passed the boys by the end of the second year," Oller says. Oller and colleagues hadn't meant to look at sex difference at all. Their primary interest is in the origins of language in infancy. If they'd had to guess, they'd have predicted female infants might make more sounds than males. But they got the same result in an earlier paper reported in Current Biology in 2020. In the new study, they looked to see if they could discern the same pattern in a much larger study. Oller says that the sample size in question is "enormous," including more than 450,000 hours of all-day recordings of 5,899 infants, using a device about the size of an iPod. Those recordings were analysed automatically to count infant and adult utterances across the first 2 years of life. "This is the biggest sample for any study ever conducted on language development, as far as we know," Oller says. Overall, the data showed that male infants made 10 per cent more utterances in the first year compared to females. In the second year, the difference switched directions, with female infants making about 7 per cent more sounds than males. Those differences were observed even though the number of words spoken by adults caring for those infants was higher for female infants in both years compared to males. The researchers say it is possible male infants are more vocal early simply because they are more active in general. But the data do not seem to support that given that the increased vocalisations in male infants go away by 16 months while their greater physical activity level does not. But the findings might fit with an evolutionary theory that infants make so many sounds early on to express their wellness and improve their own odds of surviving, Oller suggests. Why, then, would male infants be more vocal than females in the first year and not later? "We think it may be because boys are more vulnerable to dying in the first year than girls, and given that so many male deaths occur in the first year, boys may have been under especially high selection pressure to produce vocal fitness signals," Oller says. By the second year of life, as death rates drop dramatically across the board, he added, "the pressure on special fitness signaling is lower for both boys and girls." More study is needed to understand how caregivers react to baby sounds, according to the researchers. "We anticipate that caregivers will show discernible reactions of interest and of being charmed by the speech-like sounds, indicators that fitness signaling by the baby elicits real feelings of fondness and willingness to invest in the well-being of infants who vocalize especially effectively," Oller says. "We wonder how caregivers will react to speech-like sounds of boys and girls. But they may have to be told which infants are which, because we don't even know if sex can be discerned in the vocalisations alone."Also Read: High blood pressure damages healthy kidneys: Study This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/ reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

03 June,2023 04:37 PM IST | Washington | ANI
By finding a balance that suits your capabilities and lifestyle, you can reap the long-term benefits of cycling for your overall health and well-being. Photo Courtesy: iStock

'Cycle 30 minutes to prevent cardiac problems', says doctor

June 3 of every year marks World Bicycle Day. This day seeks to highlight the importance of bicycling to both, the environment and our overall wellbeing. It is one of the most reliable, affordable and easy forms of physical exercise offering multiple physical and mental health benefits. On World Bicycle Day 2023, we look at some of the common health benefits of cycling as shared by an expert. Dr Ashish Khanijo, MBBS, MS-General, Surgery, DNB - Cardiothoracic Surgeon, Cardiologist, Ruby Hall Clinic, Pune says, “Health benefits with any kind of active exercise is fairly well known. However, there are a few of these exercises like cycling that are especially beneficial to the heart and the lungs. Cycling is a dynamic, aerobic, isotonic form of exercise. Not only this, but cycling also provides for active toning of the skeletal muscles.” Cycling is probably the easiest form of exercise that does not require any training. As children, most of us have cycled for hours feeling the excitement of riding. Why should we then stop now, especially when it offers great health benefits and helps us stay fit? Khanijo says, “There is no specific age to start cycling. As long as there are no pathological reasons to not cycle, one can cycle daily to stay fit, mentally and physically. Depending on the age and stamina, one can cycle from a couple of kilometres to almost 20-25 kilometres for a period of 2 hours.”  Cycling is a low-impact, accessible form of exercise that offers numerous physical health benefits. From cardiovascular fitness to strength and endurance, cycling can greatly contribute to one's physical health. Here are some key advantages: Cardiovascular healthCycling is an excellent cardiovascular exercise that strengthens the heart and improves blood circulation. Regular cycling reduces the risk of cardiovascular diseases, such as heart attacks, strokes, and high blood pressure. Good for the joints Unlike high-impact activities, cycling is gentle on the joints, making it suitable for individuals with conditions such as arthritis or joint injuries. It provides a low-stress workout that enhances mobility without putting excessive strain on the joints. Muscle toning and strengthCycling engages various muscle groups, including the legs, core, and glutes. It helps tone and strengthen these muscles, leading to improved overall body strength and stability. Weight managementCycling is an effective calorie-burning exercise that aids in weight management. Regular cycling, combined with a balanced diet, can contribute to healthy weight loss or maintenance.  Moderate-intensity exerciseAim for a minimum of 150 minutes of moderate-intensity aerobic exercise per week, which can be fulfilled by cycling for 30 minutes on most days of the week. This level of activity helps improve cardiovascular health, maintain a healthy weight, and reduce the risk of chronic diseases.  Intensity VariationIncorporating intervals of higher-intensity cycling into your routine can provide additional cardiovascular benefits and enhance overall fitness. For example, alternating between periods of moderate cycling and short bursts of more intense pedalling can help improve aerobic capacity and increase calorie burn. Besides physical benefits, cycling has a profound impact on mental health too: Stress reductionEngaging in regular cycling helps reduce stress levels by releasing endorphins, often referred to as the "feel-good" hormones. This natural mood booster can alleviate anxiety, depression, and promote a sense of calm. Mood elevation Cycling stimulates the production of serotonin, a neurotransmitter responsible for regulating mood. Increased serotonin levels can improve mood, combatting symptoms of depression and boosting overall mental wellness. Cognitive functionRegular cycling promotes increased blood flow to the brain, providing it with essential oxygen and nutrients. This improved circulation enhances cognitive function, memory retention, and overall mental acuity. Stress relief and relaxation Cycling outdoors allows individuals to immerse themselves in nature, promoting a sense of tranquillity and reducing mental fatigue. The rhythmic motion of cycling can be meditative, providing a much-needed break from the pressures of daily life. There are a few things one must consider before starting out to yield positive outcomes: Listen to your bodyIt is important to listen to your body's signals and adjust your cycling duration and intensity accordingly. If you experience excessive fatigue, muscle soreness, or joint pain, it may be a sign that you need to reduce your cycling duration or take rest for a few days. Individual factorsKeep in mind that individual factors such as age, fitness level, underlying health conditions, and personal goals can influence the appropriate duration of daily cycling. Consulting with a healthcare professional or a certified fitness trainer can provide personalized guidance based on your specific needs and circumstances. Start slowIf you are new to cycling or have been inactive for some time, it's advisable to start slow and gradually increase your cycling duration and intensity over time. This approach allows your body to adapt and reduces the risk of injuries. Hydrate yourselfOne should drink plenty of water and maintain a balance of electrolytes as cycling causes a lot of sweating leading to loss of water and salts from the body. Carrying a bottle of plain water, fresh lime water, or any juice is a good idea when cycling. Khanijo says, “The primary goal is to make cycling a sustainable and enjoyable part of your routine. Strive for consistency rather than pushing yourself beyond the body’s capacity. This may lead to burnout or injury. By finding a balance that suits your capabilities and lifestyle, you can reap the long-term benefits of cycling for your overall health and well-being.”  Also Read: Want to lose weight without hitting the gym? These tips are all you need for your workout plan at home

03 June,2023 03:47 PM IST | Mumbai | Aakanksha Ahire
Representational images. Pic/iStock

Is mental health support a key element of inclusive work culture?

A decade ago, conversations around mental health support at the workplace were simply swept under the corporate carpet. The stigma around depression, anxiety, and stress was so prevalent that these issues were not even acknowledged. But today, 81 per cent of workplaces have increased their focus on employee mental health. As we peel back the layers of corporate norms, it becomes evident that mental health support stands as an irreplaceable pillar in creating an environment where every employee can thrive. Just as the human mind holds endless potential, embracing mental health support is the key to unlocking the untapped potential within each individual. We are all a combination of our experiences, the expectations we have of ourselves, and those that people have of us, and sometimes it is natural to be overwhelmed. How each one of us reacts to these stimuli is different, and that is what makes us unique. Investing in employee well-being is the first and most important step in fostering such individuality and building a great organisation. The World Health Organization estimates that depression and anxiety disorders cost the global economy approximately $1 trillion per year in lost productivity. Investing in mental health support not only benefits individual employees but also yields significant economic returns, creating a win-win scenario for both employees and organisations. Breaking the Stigma and Fostering AcceptanceOnly 13 per cent of employees feel comfortable discussing their mental health in the workplace. According to a study by the National Alliance on Mental Illness (NAMI), 9 out of 10 employees who experienced mental health challenges reported facing stigma in their workplace. This stigma often leads to employees hiding their mental health conditions and delaying seeking help, impacting their well-being and productivity. Picture a workplace where individuals feel seen, heard, and supported. A place where every employee is working towards growing the business, unhindered by the stigma associated with mental health challenges. Leading new-age businesses, our actions and values set the tone for the entire organization. Hence, the onus is on the leadership to actively break down the stigma surrounding mental health. This will further inspire a ripple effect, empowering others within an organization to do the same. We need to create an environment where employees can thrive, leading to enhanced productivity and optimal performance. This encourages diverse viewpoints, creativity, and collaboration, leading to breakthrough ideas and solutions. When employees feel safe to express themselves authentically, they can contribute their unique talents and experiences to the collective success of the organization. Enabling equal access to resourcesIndian workplaces have come a long way when it comes to de-stigmatizing conversations around mental health challenges. In the face of "the 2020 pandemic", mental well-being took centre stage, and workplaces started embracing mental health support policies. The industry has taken a step forward in not just acknowledging but also providing resources that are accessible, equitable, and culturally sensitive. As an ecosystem, we need to position ourselves as an ally in the mental health journey of our employees and remove barriers to access such as cost, stigma, and logistical challenges. Around 80 per cent of Indian companies have gone the EAP (Employee Assistance Program) way to offer access to trained professionals. They help employees address personal and work-related challenges, reduce stress, and improve overall well-being. New-age companies are revisiting, rehauling, and restructuring their policies to incorporate mental health support as an integral part. This includes providing flexible working hours, paid mental health leave, and additional health insurance coverage for mental health treatments. Such policies ensure that employees have the necessary resources and support to prioritize their mental well-being. Acing the talent attraction and retention gameThe younger workforce of today is drawn in by an organisation's progressive and inclusive cultural code. They seek more than just a paycheck; they yearn for a workplace that values their holistic needs and provides a supportive environment. Today's generation appreciates diversity and seeks to be a part of a company that embraces different backgrounds, opinions, and experiences. Prioritizing diversity and inclusion in hiring, leadership, and decision-making processes increases the appeal of companies to the younger workforce. It is important to remember that collaboration and innovation are fostered by an inclusive culture. According to a report by the World Health Organization (WHO), for every dollar invested in mental health treatment, there is an average return of $4 in improved health and productivity. This highlights the significance of providing accessible mental health resources to employees, as it not only benefits individuals but also contributes to overall organisational success. Our mental health support policies act as a value addition, drawing in the best and brightest minds who are eager to contribute their skills and expertise. Once they join our organization, these policies become the glue that keeps them engaged, committed, and loyal. By offering resources such as counselling services, flexible work arrangements, and mental health leave, we create an inclusive culture that meets their needs beyond the industry's tick boxes. I believe that investing in mental health support and promoting a culture that does not discard young minds not only attracts young talent but also cultivates a team of empowered individuals who are motivated to grow and thrive. Creating workplaces "Where the mind is without Fear"A recent report by Indeed titled- "Where the mind is without fear", states that a psychologically safe environment is a key component of diversity, inclusion, and belonging (DI&B) efforts. While devising policies for an all-inclusive workplace environment, we need to remember that mental health is not one-size-fits-all. Right now, we are all operating in a piecemeal manner, providing Employee Assistance Programmes (EAPs), counselling sessions, and interventions aimed at alleviating stress and improving motivation and productivity. But due to the unconscious biases at play, we are collectively running behind to reach the desired outcome. The need of the hour is to devise a compelling policy and cultural framework for mental health support and to make it the core of every organizational structure. Employees who receive mental health support and engage in self-care activities are better equipped to manage stress, make effective decisions, and maintain focus on their work responsibilities. Over the past decade, workplaces have made significant strides in addressing mental health challenges. The once prevalent stigma surrounding mental health is slowly being dismantled, creating an environment where every employee can thrive. Organisations now understand the economic and personal benefits of investing in mental health support. By taking proactive steps to provide mental health support, we can unlock the untapped potential within each individual. The focus should be on creating a future where mental health support is integrated into the fabric of every organization, allowing employees to flourish and contribute their best. Also Read: Discover rare first editions and vinyl at this thrift bookshop in Mumbai This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/ reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

03 June,2023 11:48 AM IST | New Delhi | IANS
Apart from these proven techniques that have been passed on from generation to generation, you must include nutrient-rich foods in your daily diet to reverse grey hair. Image Courtesy: iStock

Mid-Day Premium An expert guide to reverse grey hair with natural remedies

Spotting grey hair can be a stark reminder of ageing. Throughout the lifespan of a human, hair strands go through a natural cycle of regeneration and death. As we age, hair follicles become weak and begin to produce less colour. Thus, appears the inescapable greyness of hair. The question arises, what causes grey hair? The answer is the pigment melanin in the hair follicle, which is responsible for hair colour. As we age, this pigment depletes, turning our hair grey or white. The sight of grey hair is often dreaded as people conceal it with artificial hair colours. While they manage to cover it up with blazing shades, the chemicals in artificial colour can be detrimental to hair growth. These chemicals weaken the hair follicles causing hair breakage, split ends, frizzy hair, itchy scalp and hair loss. For ages, pure and natural dyes have been used to reverse the greying of hair. To learn about other natural remedies that can prevent the greying of hair, Midday Online spoke to the beautician Radhika Iyer Talatiwho is also the founder of Anahata Organic. Here is what she recommends:  “Today, the market is flooded with diverse varieties of hair colour products. These products contain a host of chemicals and questionable ingredients which the ordinary consumer is left to use. Not only does it confuse them but also stresses them about what works and what does not. It is vital for us to also know that ageing, vitamin deficiency, oxidative stress, chain-smoking, regular exposure to chemical dyes and mental stress are among the main reasons for greying of hair”, says Talati. She adds that genetics is also known to be a contributor to premature grey hair. Identifying the causes of grey hairReversal of greying hair is fairly simple if you can narrow down the factors causing the greyness. For example, you could be developing grey hair due to vitamin deficiency. In this case, increasing the intake of a certain vitamin can help reverse grey hair almost instantly. Similarly, if it's apparent stress that is leading to grey hair, then meditating and including antioxidant-rich foods in your diet can restore your original hair colour faster than you think. Research also shows that cutting down on smoking and drinking also reduces anxiety and oxidative stress. Avoiding the use of harsh chemicals or blow-drying your hair too often will also help reverse grey hair. Even though grey hair due to genetics cannot be reversed, there are ways to reduce that effect to a large extent. Here are five ways you can practice reversing grey hair naturally. These tips are also effective in strengthening your hair: 1. Traditional oil decoction formula to regrow hair and reverse greyingThis age-old tradition from Ayurveda recommends massaging your hair with a mixture of 4 tablespoons of almond oil, 2 tablespoons of coconut oil, 1 tablespoon of sesame oil and 1 tablespoon of castor oil. All you need to do is warm this combination over a medium flame, let it cool and add to it 1/2 tablespoon of lemon juice and 1 tablespoon of amla juice. To this mixture, add 1 tbsp of fenugreek powder. Cool, strain and apply generously all over the scalp at night. Use a natural shampoo to wash it off in the morning. When used at least three times a week and left for about 4 to 5 hours, one can observe noticeable results. Practicing this regularly will reduce grey hair, strengthen hair follicles and add plenty of vital nutrition to the scalp. 2. Rubbing onion juice onto the scalpOur grandmothers would always use onion juice on their scalps for great hair. Red onions are an effective way to control grey hair and boost hair growth. The juice of an onion raises catalase, an enzyme that is responsible for darkening hair. Not only that, onion juice is a great source of hydration for the scalp and is known to add shine and glow to the hair. Simply mix 3 tablespoons of onion juice, 1 tablespoon of lemon juice and 1 tablespoon of sesame oil in a bowl. Massage your scalp with this combination and wash after 30 minutes with a natural shampoo. You will notice visible results within a month. 3. Using Curry LeavesCurry leaves contain precious Vitamin B that restores the pigment melanin in the hair follicles. Using Curry leaves in many forms is known to reverse and prevent further greying. Beta-Keratin present in curry leaves prevents hair fall and helps keep the scalp hydrated. Prepare a paste by grinding 20 grams of fresh curry leaves with some water. A. Mix this with 2 tablespoons of curd and apply this all over your head and hair. Leave it on for 25 minutes or more and wash off with a natural shampoo. B. Boil 20 grams of curry leaves, 1/2 tablespoon of fenugreek seeds and 1 tablespoon of nigella seeds in about 5 tablespoons of coconut oil until the leaves turn black. Strain and use this oil on your hair.  Boil a cupful of curry leaves in a cup of oil till they turn black. Cool, strain and store. Massage into hair 2-3 times a week. Leave overnight and repeat at least 3 times a week. The results will amaze you. 4. Coffee or Tea with Castor Oil and Henna leavesWe all know that henna is a natural colorant and conditioner. It has been used traditionally as a scalp cleanser and hair conditioner. It is also used as a natural pigment for reversing grey hair. The tannic acid and many other antioxidants present in coffee and tea, when combined with henna are known to give excellent results turning grey hair back to its natural colour. All you need to do is add 1 tablespoon of coffee powder or 1 tablespoon of tea to boiling hot water. Let this infuse for about 5 minutes on a medium flame. Strain, cool and make a paste by adding an appropriate amount of henna powder to this liquid. Let it rest for about 3 to 4 hours. Mix in a tablespoon of castor oil in this paste and apply liberally all over your hair as well as the scalp. Leave this on for an hour and wash off using a natural shampoo. Adding a natural dark hue to the hair, stimulates hair growth and strengthens it, giving it a shine. This remedy not only reverses grey hair but also leaves your hair feeling stronger and shinier than before. 5. Shikakai, Brahmi, Black Pepper and Lemon hair packAnother ancient technique to reverse grey hair and induce vital nutrients into the hair follicles is the use of shikakai, pepper and lemon. Black pepper is known to have numerous benefits for the hair and apart from just helping maintain the natural colour of your hair it also promotes hair growth. Shikakai helps reverse grey hair effectively while strengthening hair follicles and lemon keeps harmful bacteria and dandruff away. Together, they provide vitamins A, B12, D, E and biotin. Important minerals such as zinc, iron, magnesium and copper are also present in this concoction that can help keep your hair healthy and long. All you need to do is mix 1 tablespoon each of shikakai powder, brahmi powder, freshly ground black pepper and lemon juice with half a cup of homemade curd. Mix these well and massage them into hair and scalp. Leave the paste on for about an hour and wash it off with lukewarm water. Do this at least three times a week for incredible results. Nutritional tips to avoid greying of hair Apart from these proven techniques that have been passed on from generation to generation, you must include nutrient-rich foods in your daily diet that can help reverse grey hair. Consume amla juice when in season and have dried amlas when they are not in season. Remember to avoid preservative-laden foods and stay away from fast food as much as you can. Avoid consuming Maida or fine flour, you will be surprised how clean your body will start to feel. High sugar, saturated fats and too much salt or sodium are also disruptors of hair health. Stick to simple living, turn back to your roots and keep yourself active both mentally and physically. These simple yet extremely effective tips will help you discover the long-lost dark, healthy and bouncy mane that you deserve to sport every single day. Also Read: What is ‘placemaking’ and how it evokes human-nature interaction at workplaces

02 June,2023 09:32 AM IST | Mumbai | Ainie Rizvi
Low-carb diets have become trendy in recent years and have been recognized as a dietary strategy to improve glucose control. Photo Courtesy: iStock

Low-carb breakfast can help manage sugar levels in people with Type 2 diabetes

For people with Type 2 diabetes (T2D), making small adjustments to breakfast may help in controlling their blood sugar levels, according to an international team of researchers led by UBC Okanagan academics. In the UBCO Faculty of Health and Social Development, Dr Barbara Oliveira collaborates on research projects with Dr Jonathan Little's Exercise, Metabolism and Inflammation Lab. Their most recent research, which was just published in the American Journal of Clinical Nutrition, supports the idea that people with T2D can benefit from switching from a traditional western-style low-fat breakfast like oatmeal, toast and fruit to a low-carb meal higher in protein and fat, like eggs with bacon or cheese. In fact, changing just one meal helped keep the blood sugar in check. "We're not talking about a complete diet overhaul," says Dr Oliveira. "One of many complications for people living with T2D is rapid or large increases in blood glucose levels after a meal. Our research indicates a low-carbohydrate meal, first thing in the morning, seems to help control blood sugar throughout the day." Controlling glucose levels is critical for reducing the complications of T2D including inflammation and cardiovascular disease--the major cause of morbidity in patients with T2D. "Treatment strategies that can help lower post-meal glucose swings and rapid changes in glucose are crucial to managing this condition," she adds. "We've determined that if the first meal of the day is low-carb and higher in protein and fat we can limit hyperglycemic swings." Low-carb diets have become trendy in recent years and have been recognized as a dietary strategy to improve glucose control, Dr Oliveira explains. However, similar to all diets, it's tough to follow, especially long term. Instead of asking patients to commit to every meal being low-carb, she and Dr. Little examined the idea of making just the first meal of the day low-carb to see how that impacts diet adherence, and more importantly, blood glucose levels. Their 12-week study had 121 participants split into two groups. One was advised to eat from a selection of low-carb breakfasts containing approximate amounts of 8g of carbohydrate, 25g of protein and 37g of fat while the other was advised to eat from a selection of low-fat higher-carb options containing about 56g of carbohydrates, 20g of protein and 15g of fat. All the breakfast options in both groups provided 450 calories. Participants had a variety of breakfast choices and were required to upload a photo of their meal, which was reviewed by a study dietitian to confirm compliance. All participants were provided with a continuous glucose monitoring device they wore throughout the study and also undertook A1C blood tests, before and after the 12 weeks, to measure their average blood sugar levels. They also measured their weight and waist circumference at the beginning and end of the trial. As the study continued they reported feelings of satiety, energy and activity levels. Dr Oliveira notes while there were no significant differences between the low-carb and another group for weight, body mass index or waist circumference, the low-carb group did see a reduction in blood sugar levels and some were able to reduce their glucose-lowering medication. The upward and downward swings in blood glucose levels, known as glycemic variability, with the low-carb group were also significantly lower, suggesting the benefits of a low-carbohydrate breakfast for stabilizing blood sugars throughout the day. One additional interesting finding was that people who had low-carb breakfast self-reported lower calorie and carbohydrate intake at lunch and during the remainder of the day. This could suggest that a breakfast rich in fat and protein, while lower in carbs, can impact daily eating habits. "Having fewer carbs for breakfast not only aligns better with how people with T2D handle glucose throughout the day, but it also has incredible potential for people with T2D who struggle with their glucose levels in the morning," she adds. "By making a small adjustment to the carb content of a single meal rather than the entire diet, we have the potential to increase adherence significantly while still obtaining significant benefits." Also Read: Diabetes on rise among youngsters in India: Expert speaks about the reasons behind the chronic disease and ways to manage it This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/ reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

01 June,2023 04:29 PM IST | Washington | ANI
Between 2020 and 2021, the number of weight-loss surgeries among youth jumped 19 per cent. Photo Courtesy: iStock

New study show rise in weight-loss surgeries among children, teenagers

A new study has found that weight-loss surgeries among adolescents have increasingly become a part of obesity treatments in the US. The findings, published in the JAMA Pediatrics, showed the number of metabolic and bariatric surgeries completed among youth ages 10 to 19 has been on the rise since 2016. Between 2020 and 2021, the number of weight-loss surgeries among youth jumped 19 per cent. "This data shows us that adolescents and their families are indeed interested in pursuing surgery as a treatment option if they are given access and a good candidate," Sarah Messiah, professor and paediatric obesity researcher at UTHealth Houston School of Public Health was quoted as saying by CNN health. "Many studies show that cardiometabolic disease risk factors track strongly from childhood into adulthood," she said. According to the US Centers for Disease Control and Prevention, Childhood obesity is a "serious problem" in the US, affecting about one in five children and teenagers -- nearly 15 million between ages 2 and 19. Gastric bypass and other weight loss surgeries -- known collectively as bariatric surgery -- involve making changes to the digestive system to help you lose weight. Bariatric surgery is done when diet and exercise haven't worked or when you have serious health problems because of your weight. The study showed that barriers to access, including low referral rates from paediatricians and poor insurance coverage meant that these weight-loss surgeries have remained underutilised. But earlier this year, the American Academy of Pediatrics published new guidelines for the treatment of obesity -- the first update in 15 years. The new guidelines urge prompt use of behaviour therapy and lifestyle changes and, for the first time, recommend surgery and medications for some young people. Teenagers with severe obesity in particular should be evaluated for surgery, the report said. Also Read: Dermal fillers are on the rise among young Indians, here's why This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/ reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

01 June,2023 04:03 PM IST | New York | IANS
Snehal picked Vasudev as her avatar and experimented with musical notes to create an anti-tobacco anthem. Photo Courtesy: Snehal Kshirsagar

Mid-Day Premium How Mumbai’s slum champion Snehal Kshirsagar uses music to battle tobacco abuse

You reach Snehal Kshirsagar’s house after a short trek through Charkop’s clustered slum pocket. Known as Babrekar Nagar, the slum is home to numerous chawls endowed with blue tarpaulins and dish TV antennas. At the heart of Prabhat Chawl within Charkop, is Snehal’s 10x10 shanty, where she is gearing up for her next big gig. The 14-year-old is set to raise awareness about the ill effects of chewing tobacco through her self-composed anthem.  As we enter the shanty, the mirror reflects her disguised avatar of Vasudev, the agent of social change in Maharashtra. To catch the attention of her community, she has decided to take on the avatar of Vasudev which is a revered community of Krishna worshippers, found mainly in Maharashtra. Vasudev essentially wanders through villages and towns to spread the message of healthy living and refraining from social evils like intoxication. On World No Tobacco Day, Midday Online spoke to Snehal Kshirsagar, who is innovating with the power of music to campaign against the chewing of masheri, a locally sourced tobacco. Genesis of her performance avatarHarking back to bygone days, Snehal reminisces about travelling to her native town, Pandharpur with her mother. The town is a famous pilgrimage destination, on the banks of Candrabhaga River, near Solapur city. She recalls a memory from Pandharpur that is deeply etched in her mind. “Vasudev used to visit my village and sing meaningful hymns about social conduct. Through their lyrics, I developed a sense of purpose and direction in my life.” It was Vasudev’s riveting persona that inspired Snehal’s performance avatar. She believed that Vasudev has a connection with her community and it can serve as a medium for her message. “When I began composing the anti-tobacco campaign, I knew I had to keep his perspective in mind. His figure is the one that people look up to and his words are those they repeat.” To continue with her disguised look, she applies black paint on her forehead and cheekbones. She circles off the black with a white ring to make the look more prominent. Next, she crowns herself with a peacock feather hat that compliments her white frock. The look is now complete. Snehal finally resembles the local God, Vasudev, who survives on the alms donated by villagers. Charkop’s favourite tobacco MasheriKnown as masheri, this raw form of tobacco is a hot favourite amongst the slum dwellers of Charkop. “In my locality, women are majorly addicted to chewing masheri. Come mornings, they head to the local shops and procure a day’s quota of masheri. Next, they heat it on the pan along with harmful elements like sawdust for hours. This turns it more carcinogenic and toxic which women like to chew all day long. Unfortunately, they believe that chewing masheri makes their day’s labour bearable”, revealed Snehal. There are various myths circulating around masheri in the slums. Some of the popular ones are that it helps in curbing hunger and improves oral health. Hence, women place it inside their mouths and leave it there for hours. This is one of the leading causes of cancer among Mumbai's slum population. Chanda Aunty is one of her neighbours who cannot go by a single day without chewing masheri. Joining Chanda are more local women who sit outside their shanties and consume tobacco while working on their daily tasks. Not only elderly women from Prabhat Chawl but several teenage boys from Snehal’s school rampantly consume this tobacco. Snehal attends 10th standard at the Charkop Marathi Sector 1 Secondary School. “As soon as the school gets over, boys from my class gang up and score packets of masheri. They are in the age group of 14-16 and are brazen to do what they like. Their addiction goes unchecked due to a lack of awareness among our teachers and parents”, shares Snehal. Sensitisation towards anti-tobacco campaignThe 3-foot-wide alleys of Prabhat Chawl are home to the newest arrivals of Mumbai. Here, Snehal resides with her grandmother, mother and two brothers (one younger and one older) in a one-room shanty. They have one Android phone which is shared by the entire family and is also the one her mother takes to work. Though her family refrains from tobacco, her neighbourhood is filled with the foul smell of masheri cooking on the pans. To sensitise adolescents against tobacco abuse, a city-based NGO, Salaam Bombay Foundation launched the Preventive Health Education Programme in Mumbai’s slums. The theme for this year’s World No Tobacco Day is “We need food, not tobacco”. To build on this theme, the students of Salaam Bombay Foundation were educated on different aspects of health at a pivotal time in their lives (between grades 7 and 9). This program involved workshops on resistance to tobacco use, awareness about nutrition, and looking out for their mental well-being. Empowered with this knowledge, Snehal began to spearhead the change within her community. She became one of the Health Monitors of the Salaam Bombay Foundation which spreads awareness against tobacco consumption and switching to nutritious meals. The power of music to campaign against tobacco“I despised the sight of women chewing masheri. However, I always wondered if I could discourage them from doing so”, informed Snehal who was keen to bring a change in her community. Filling in this gap, Salaam Bombay Foundation equipped Snehal with the rightful knowledge. At the workshop, Snehal learnt about the ill- effects of tobacco and began working on a lyrical composition with a divine touch. Snehal picked Vasudev as her avatar and merged her musical notes to create her anti-tobacco anthem. The lyrics of her composition represent the toxicity of chewing masheri. In Marathi language, she sings: “Vasudev is here, to awaken your social conscience. This life is precious, the value of your life is one in a million. Hey, you quit tobacco now, don't be late, time is too short. Vasudev said that addiction is not good. Gutkha, tobacco is deadly. Hear the voice of Vasudev, hear the higher being in you.” At the young age of fourteen, Snehal is fully aware of what tobacco does to the body. “Smoking and chewing tobacco attacks our lungs and infuses hazardous chemicals in our body. It causes coughing, wheezing and leads to oral cancer.” Today, Snehal disguised as Vasudev, goes about her locality every fortnight to reinforce the message against tobacco. Often, she is accompanied by her friend while performing at the rickshaw stand outside her chawl, Malwani area and at her school. It is her conviction in the power of music, that has yielded results for Snehal. She proudly shares how her efforts have brought a change of heart among two South Indian women in her locality. “Every once in a while, I cross paths with them and they thank me for freeing them from the evils of tobacco. It motivates me to keep going.” Also Read: World No Tobacco Day: Cancer surgeon warns against smoking, here's how to detect oral cancer early

01 June,2023 09:53 AM IST | Mumbai | Ainie Rizvi
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Use these 6 natural herbs for youthful and glowing skin

Every one of us looks for ways to retain a youthful skin and often resort to a variety of products in pursuit of that ideal skin. However, it may not always help. Over the years, there are various natural remedies that have been used to protect the skin. The ancient knowledge of Ayurveda has reemerged, offering a revitalising and holistic approach to skincare in a world dominated by modern beauty products and invasive surgeries. The traditional Indian medical system known as Ayurveda understands that true beauty comes from taking care of the body from the inside out. It offers a time-tested treatment for aged skin that values authenticity and sustainability by utilising natural treatments and antiquated traditions. Ageing skin requires care, especially natural solutions that don't let your skin give away your age. Let's explore the various herbs that help achieve a youthful glow, better known as the age-old Nani ke nuskhe: Turmeric: A golden treasure for skin enhancementThis radiant spice has potent anti-inflammatory and antioxidant properties. Create a golden paste by mixing turmeric powder with honey or milk, and gently apply it to your face. Let the transformative magic unfold as the paste reduces inflammation and reveals a newfound radiance. Simply apply the turmeric-infused paste on your face and leave it on for 15-20 minutes. Rinse off the mask with warm water and unveil an improved complexion that beams with natural beauty. Aloe Vera: Nature's soothing elixir for the skinKnown for its soothing and healing properties, aloe vera replenishes lost hydration and leaves your skin soft, supple, and glowing with vitality. Simply apply fresh aloe vera gel directly to your skin and experience its refreshing and nourishing effects. Gently massage the cool gel onto your face. Regular use of aloe vera gel can even help reduce the appearance of fine lines and wrinkles, giving you a youthful and radiant complexion. Neem: Nature's shield for clear and healthy skinNeem, within the realm of skincare, is known for its potent antibacterial and antifungal properties, making it a remarkable guardian for your skin. This extraordinary plant offers a natural solution for treating acne and combating various skin infections. Harnessing its power is as simple as creating a paste by grinding neem leaves with water and gently applying it to the affected area. Allow the paste to work its magic, leaving it on for 15-20 minutes before rinsing it off. Experience the transformative effects of neem as it revitalises your skin, providing a natural solution for clearer and healthier skin. Sandalwood: A fragrant marvel for rejuvenating skinSandalwood is versatile, catering to different skin types. For dry skin, create a paste with sandalwood powder, honey, and olive oil. It soothes and moisturises skin, revealing a refreshed complexion. For oily skin, mix sandalwood powder, fuller's earth, and lemon juice. It absorbs excess oil and unclogs pores, leaving a fresh, matte finish. Apply the mask to your skin and leave it on for 10-15 minutes. After the mask has dried, rinse it and experience the transformative effects of sandalwood for radiant and balanced skin. Rosewater: A gentle elixir for skincareRevitalise your skincare routine with the enchanting properties of rosewater. This gentle elixir effortlessly harmonises with your skin, maintaining its pH balance and providing hydration. Experience its calming effect as it reduces redness and reveals a refreshed complexion. Enjoy the convenience of using rosewater as a natural makeup remover, allowing your skin to breathe freely and luxuriate in the soothing essence of roses. Let rosewater be your go-to elixir, infusing your skincare ritual with its delicate and transformative touch. Shatavari: Nourishing elixir for skin healthIn the realm of Ayurvedic skincare, Shatavari, though not traditionally used directly on the skin, holds incredible potential to nurture your skin's health through internal consumption. Available in various forms, such as powder, capsules, or liquid extract, Shatavari is often consumed as a dietary supplement. Indulge in the timeless ritual of taking Shatavari orally, either with warm water or milk, to unlock its holistic benefits. In a world where quick fixes and instant results often dominate, Ayurveda offers a profound reminder to slow down, connect with nature, and prioritise our inner health. The Ayurvedic beauty secrets for ageing skin provide a natural and sustainable path to achieving youthful, glowing skin that radiates from the inside out. It's the perfect time to incorporate the goodness of Ayurveda into our daily beauty regimes. (Dr. Kriti Soni, head of R&D, Kapiva)Also Read: Dermal fillers are on the rise among young Indians, here's why This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/ reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

31 May,2023 10:42 PM IST | Mumbai | IANS
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Here are 8 factors causing wrinkles on your skin

People dread wrinkles because we are aware that they cause ridges, folds, or creases in the epidermis of the skin. As we become older, the wrinkles develop naturally on our skin due to various reasons. It is however perfectly normal to have wrinkles on your skin. As we age, our skin normally becomes drier, thinner, and less elastic. However, it may be concerning if you start to wrinkle before your time. First of all let's understand why we get wrinkles, its causes and their prevention from the experts: Sunlight exposureWrinkles are primarily brought on by the sun. UV radiation from sunlight can penetrate the deepest layers of skin and break down collagen, which makes the skin less flexible. Wear sunscreen that is suited for your skin type whether you are inside or outside, whether you are driving or just relaxing by the window. Given the previous weather, SPF 30 or higher is recommended. The sun's indirect rays might also lead to wrinkles. People who work in the sun are more likely to get early wrinkles. Wrinkles may be avoided by donning clothes that covers the skin, such as long sleeves or a hat. Smoking and alcohol consumptionSmoking often reduces the blood flow to the skin, accelerating skin ageing. Skin is dried out by alcohol. As a result, the skin loses strength and flexibility. Wrinkles start to develop as the skin begins to sag. So for the sake of your skin, give up drinking and smoking. SquintingSquinting and particularly active facial movements like furrowing your brows and frowning can also contribute to wrinkles. When you squint, your face muscles stiffen up. Dr Karuna Malhotra, Cosmetologist and Aesthetic Physician from Cosmetic Skin Clinic, New Delhi said "as a result, your skin cells become squeezed and lose their suppleness. Many individuals have a tendency to squint. But you may change this negative behaviour and stop wrinkles from forming by making conscious efforts." Stress is a key culpritDr Sandeep Babbar, Medical Director and Dermatologist from Revyve Skin, Hair and Nail Clinic, Faridabad explained "as we age, the body produces less collagen, and stress also decreases collagen production and can cause inflammation. Collagen loses flexibility and rigidity as it ages, making it less effective at promoting skin regeneration and wound healing. Both a loss of flexibility and persistent brow furrowing brought on by stress can cause wrinkles. Stress can also cause wrinkles to emerge because high amounts of the stress hormone cortisol can break down the collagen and elastin in the skin." Dry skinIf you have dry skin, you are more likely to have wrinkles. People with dry skin produce less sebum, the skin's natural moisturiser, which acts as a barrier to shield your skin from the whims of the climate. Regularly moisturise at least twice a day to prevent wrinkles because doing so prevents dryness, which reduces the likelihood that wrinkles will appear. Lack of sleepLack of sleep makes skin healing more difficult. The skin's ability to retain moisture is compromised, as well as the pH level. All of this causes insufficient collagen formation, which speeds up the development of wrinkles. Excessive cosmetic useYour skin can benefit from cosmetics, but overusing them could have the opposite effect said Dr Karuna Malhotra. They could cause rashes, edoema, clogged pores, and other unfavourable outcomes. All of them can delay the onset of wrinkles by reducing the production of collagen and sebum. Food deficienciesOn the other hand, dietary deficiencies wreak havoc on your skin, causing breakouts, rashes, dry skin, wrinkles before their time, etc. If you don't get enough vitamins, your skin may start to show it by becoming dry, pigmented, dull, or overly oily. Your face and body show the effects of the food you eat. Include vitamin C, D, B, E, and K in your diet; these nutrients are crucial for maintaining healthy skin. "People may go for a variety of treatments to get rid of wrinkles. Making lifestyle adjustments like moisturising, using sunscreen, eating a good diet, being less stressed out, exercising regularly, giving up smoking, and drinking less alcohol can help you delay or prevent wrinkles. For deeper wrinkles, a person can also require procedures like microdermabrasion, botox, fillers, chemical peels, facelifts, etc", said Dr Sandeep Babbar.Also Read: An expert guide to reverse grey hair with natural remedies This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/ reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

31 May,2023 10:29 PM IST | New Delhi | IANS
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Researchers discover how junk food may harm deep sleep

Uppsala University researchers examined how junk food impacts sleep in a new study. In random order, healthy volunteers consumed an unhealthy and a healthier diet. The quality of the participants' deep sleep had decreased after the unhealthy diet, compared to those who had followed the healthier diet. The findings of the study were published in the journal Obesity. Several epidemiological studies have found that what we eat influences how we sleep. However, few research have looked into how nutrition impacts sleep directly. One method is to have the same individual consume various diets in a random order. "Both poor diet and poor sleep increase the risk of several public health conditions. As what we eat is so important for our health, we thought it would be interesting to investigate whether some of the health effects of different diets could involve changes to our sleep. In this context, so-called intervention studies have so far been lacking; studies designed to allow the mechanistic effect of different diets on sleep to be isolated," said Jonathan Cedernaes, Physician and Associate Professor in Medical Cell Biology at Uppsala University. Previous epidemiological studies have shown that diets with greater sugar content, for example, are linked to poorer sleep. Yet sleep is an interplay of different physiological states, as Cedernaes explains: "For example, deep sleep can be affected by what we eat. But no study had previously investigated what happens if we consume an unhealthy diet and then compared it to quality of sleep after that same person follows a healthy diet. What is exciting in this context is that sleep is very dynamic. Our sleep consists of different stages with different functions, such as deep sleep which regulates hormonal release, for example. Furthermore, each sleep stage is hallmarked by different types of electrical activity in the brain. This regulates aspects such as how restorative sleep is, and differs across different brain regions. But the depth or integrity of the sleep stages can also be negatively affected by factors such as insomnia and ageing. Previously, it has not been investigated whether similar changes in our sleep stages can occur after exposure to different diets." Each study session involved several days of monitoring in a sleep laboratory. Therefore, only 15 individuals were included in the study. A total of 15 healthy normal-weight young men participated in two sessions. Participants were first screened for aspects such as their sleep habits, which had to be normal and within the recommended range (an average of seven to nine hours of sleep per night). In random order, the participants were given both a healthier diet and an unhealthier diet. The two diets contained the same number of calories, adjusted to each individual's daily requirements. Among other things, the unhealthier diet contained a higher content of sugar and saturated fat and more processed food items. The meals of each diet had to be consumed at individually adjusted times, which were matched across the two dietary conditions. Each diet was consumed for a week, while the participants' sleep, activity and meal schedules were monitored at an individual level. After each diet, the participants were examined in a sleep laboratory. There, they were first allowed to sleep a normal night, while their brain activity was measured to monitor their sleep. The participants were then kept awake in the sleep laboratory, before being allowed to catch up on sleep. Their sleep was recorded in this case, too. "What we saw was that the participants slept for the same amount of time when they consumed the two diets. This was the case both while they were following the diets, as well as after they had switched to another, identical diet. In addition, across the two diets, the participants spent the same amount of time in the different sleep stages. But we were particularly interested in investigating the properties of their deep sleep. Specifically, we looked at slow-wave activity, a measure that can reflect how restorative deep sleep is. Intriguingly, we saw that deep sleep exhibited less slow-wave activity when the participants had eaten junk food, compared with consumption of healthier food. This effect also lasted into a second night, once we had switched the participants to an identical diet. Essentially, the unhealthy diet resulted in shallower deep sleep. Of note, similar changes in sleep occur with ageing and in conditions such as insomnia. It can be hypothesised, from a sleep perspective, that greater importance should potentially be attached to diet in such conditions," explained Cedernaes. The researchers do not currently know how long-lasting the sleep effects of the unhealthier diet may be. The study did not investigate whether the shallower deep sleep may alter functions that are regulated by deep sleep, for example. "It would also be interesting to conduct functional tests, for example to see whether memory function can be affected. This is regulated to a large extent by sleep. And it would be equally interesting to understand how long-lasting the observed effects may be. Currently, we do not know which substances in the unhealthier diet worsened the depth of deep sleep. As in our case, unhealthy diets often contain both higher proportions of saturated fat and sugar and a lower proportion of dietary fibre. It would be interesting to investigate whether there is a particular molecular factor that plays a greater role. Our dietary intervention was also quite short, and both the sugar and fat content could have been higher. It is possible that an even unhealthier diet would have had more pronounced effects on sleep," noted Cedernaes. Also Read: Curd rice to carpaccio: Make these savoury dishes with mangoes this summer This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/ reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

31 May,2023 02:30 PM IST | Uppsala (Sweden) | ANI
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