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Weight gain in 20s can lead to weaker heart in old age, finds study

People who gain excess weight from their 20s are likely to have weaker hearts by the time they reach their 60s, according to a study. Scientists from the University College London (UCL) verified this by examining the links between weight gain in young and middle-aged adults and enlarged hearts that pump blood less well. This is over and above the effect of being overweight in later years, they said in the paper, published in the European Heart Journal. Alun Hughes, Professor of Cardiovascular Physiology and Pharmacology at UCL noted that early weight gain causes heart damage beyond the effects of being overweight later in life. He said that while it is known that "being overweight is associated with poorer heart health, we know little about the long-term relationship between being overweight over the adult life course and subsequent heart health". Hughes noted that the research aimed "to look at whether being overweight at earlier stages of adult life showed lasting associations with poorer heart health irrespective of people's weight in later life". The study included 1,690 people born in England, Scotland, and Wales in 1946. The participants were examined based on their body mass index (BMI), waist-to-hip ratio, and ECGs. Researchers found that elevated BMI from age 20 onwards led to higher left ventricular mass in individuals in their 60s, indicating poor heart health and increased mortality risk. A five-unit higher BMI at age 43 correlated with a 15 per cent or 27-gram increase in left ventricular mass. They added that the study included mostly white European people, so it may not apply to the global population, although Professor Hughes said there is a close link. Also Read: Can't lose weight despite a healthy home diet? Here’s what you need to know This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/ reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

17 July,2024 03:46 PM IST | New Delhi | IANS
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Prediabetes can raise risk of diabetes by 70 per cent, say experts

Prediabetes is the most ‘overlooked’ health condition, which if not reversed in time can raise the risk of diabetes by 70 per cent, said experts on Wednesday. Prediabetes is a serious condition that occurs when blood sugar levels are higher than normal, but not high enough to be considered Type 2 diabetes. The condition affects more than 130 million individuals in India and over 700 million people worldwide. Like diabetes, it can lead to life-threatening complications like a heart attack or brain stroke. “Prediabetes puts you at a greater risk of developing diabetes. If both fasting and post-glucose levels are high, the risk is the highest. The level of HbA1c determines the risk for diabetes, with the five-year risk being 50 per cent if the HbA1c is more than 6 per cent, and 25 per cent if it is between 5.7 and 6 per cent,” Dr Ambrish Mithal, Chairman, Endocrinology and Diabetes, Max Healthcare, told IANS. The HbA1c test is used to evaluate a person's level of glucose control. “The lifetime risk of developing diabetes if you have prediabetes is 70 per cent or greater,” he added. Prediabetes can be considered a warning sign by your body that your insulin levels are significantly rising or the insulin is not working properly at a cellular level often this is called “Insulin resistance” and is accompanied by abdominal obesity. Besides heart-related conditions, it can also lead to other complications like high blood pressure, kidney diseases, fatty liver disease, nerve damage, blood vessel damage, and even vision problems in some cases. Dr Shashank Joshi, Endocrinologist, at Lilavati Hospital Mumbai, calls it “a wake-up call from your body that certain habits are damaging your blood vessels and can lead to complications like heart attack or brain stroke”. “If left untreated, it can negatively impact your overall well-being. Even if you are not diagnosed with type 2 diabetes, it can still cause serious health issues such as severe damage to the kidneys, heart, nerves, and blood vessels,” he told IANS. Also Read: Beat the stress: Experts share ways to regulate the stress hormone cortisol But can it be stopped in its tracks? “Yes, it is possible to reverse or get remission of the onset of prediabetes by early detection and certain lifestyle adjustments,” said Dr Joshi. Dr Mithal said, “prediabetes can also be interpreted as ‘prevent diabetes’”. “One can reverse prediabetes to normal, or at least remain in the prediabetes range for a prolonged period of time without converting to diabetes. Up to 50 per cent cases of Type 2 diabetes can be prevented or delayed if intervention is introduced at the right time. About five to seven per cent weight loss goes a long way in improving glucose levels and reducing associated risks,” he told IANS. Early detection also plays a key role in reversing the condition. “Everyone living in India must check glucose especially above 25 if they have a family history of diabetes or their waist circumference is above 90 cm for men and 80 cm for women at least once in three years till age 40 and then every year. Ideally, both fasting and 2 hours post-meal glucose must be checked apart from 3 monthly average glucose namely Glycosylated haemoglobin,” Dr Joshi said. “If prediabetes is diagnosed, adopt simple lifestyle measures under expert medical supervision. This includes eating less, eating on time, eating right, moving or walking more, sleeping well, and stopping smoking tobacco and alcohol,” the doctor said. This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/ reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

17 July,2024 02:38 PM IST | New Delhi | IANS
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Study shows spinal muscular atrophy may raise risk of liver damage

People living with the neurodegenerative condition Spinal Muscular Atrophy (SMA) could be at a higher risk of developing fatty liver disease, according to an international study by researchers from the US, Singapore, and Scotland.  This finding suggests that SMA patients may face additional health problems over time and that its impact extends beyond the nervous system, potentially affecting other organs such as the liver. SMA is a rare genetic condition that prevents the body from producing Survival Motor Neuron (SMN) -- a protein essential for nerves that control movement. The damage in motor neurons makes them unable to send messages to the muscles, resulting in progressive muscle weakness. "Our findings show that SMA patients may be at higher risk of additional health problems over time, as the SMA gene mutation also affects other organs in the body, including the liver," said Crystal Yeo, Clinician-Scientist from A-STAR's Institute of Molecular and Cell Biology (IMCB), Singapore. The study, published in the prestigious Journal of Clinical Investigation, revealed that a genetic mutation which causes SMA, further reduces SMN protein levels in liver cells. This leads to liver impairment and their ability to break down and use fat effectively. In fatty liver disease, fat builds up in the liver leading to inflammation and damage. The disease, usually linked to heart conditions, diabetes, and obesity, is particularly concerning for SMA patients, the team said. Importantly, the study showed that editing the faulty gene in patients' stem cells to increase SMN production reversed the liver dysfunction caused by the mutation. This establishes a direct link between the genetic defect and liver problems in SMA. Earlier, we also published: Maintain hygiene, urges doctor amid rising cholera cases Hygiene is crucial to curb the cholera outbreak, currently seen in Kerala and Gujarat, said a medical expert on Sunday.   Cholera is a waterborne bacterial infection due to the bacterium Vibrio cholerae that is transmitted from one infected person to another due to contaminated water or food, especially seafood. "Once ingested, the bacteria multiply within the small intestine and produce the cholera toxins that are responsible for the symptoms of severe watery diarrhoea also called 'rice water loose stools' and severe dehydration,” Dr Sujatha Thyagarajan, senior consultant – Paediatrics & Paediatric Intensive care, Aster RV Hospital in Bengaluru, said. Kerala’s capital Thiruvananthapuram has seen a severe outbreak of cholera with reportedly one suspected death and 12 confirmed cases and 17 suspected cases are undergoing treatment. Several cases of cholera have also been reported from Gujarat and an area in a 2-kilometer radius has reportedly been declared as a cholera-affected area, under the Epidemic Diseases Act. "The rapid loss of fluids and electrolytes, if not replaced quickly, can cause death. The spread can be rapid especially when there is limited clean water supply and unsanitary conditions reaching epidemic proportions very quickly," Dr Thyagarajan said. She noted that cholera prevention is of utmost importance and requires a multi-pronged approach, adding that children and the elderly are highly vulnerable to severe dehydration, complications, and even death, and hence warrant prompt recognition and treatment. "The focus must be on improving personal hygiene and ensuring access to clean potable water. It is important to ensure there are adequate sanitation practices to avoid contamination of sewage and safe water is provided at all times," she said. She also recommended "proper cooking and safe handling of seafood". "In general, adequate personal hygiene must be maintained at all times -- hand washing with soap after the toilet and before eating food." Further, Dr Thyagarajan said once an outbreak is identified, the rapid spread must be contained aggressively through regular surveillance and prevention methods. "The main treatment of Cholera is timely rehydration through ORS (oral rehydration solution) or intravenous rehydration to replace the rapid fluid and electrolyte loss," she said, adding that antibiotics can help in severe cases. This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/ reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

17 July,2024 11:08 AM IST | Mumbai | IANS
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Monsoon Skincare: Follow these tips for healthy skin during rainy season

The monsoon season brings with it the necessity and opportunity to implement specific lifestyle practices. While people are quick to adopt weather-appropriate clothing and choose monsoon travel destinations, an often overlooked area that requires special attention during monsoon is skincare. The humid weather causes several challenges for the skin like dampness and clogged pours, making implementation of special monsoon skincare measures important. In a conversation with, Dr. Taniyaa Bakshi, a Delhi-based homeopathy expert and director of Bakson Group, shares the importance of monsoon skincare and essential tips one must follow to keep the skin radiant and healthy during rainy season. Why is it important? Seasonal change necessitates special skincare practices. “Monsoon means more humidity. When there’s more humidity, our skin tends to produce more sebum (an oily secretion that hydrates the skin). That’s why, in monsoon, the skin feels damp and dewy. Now the problem is that with too much humidity, bacteria can also start accumulating on your skin. It also attracts dirt which stays on the skin for a long time. So, taking care of your skin is extremely essential,” Dr. Bakshi explains. Monsoon Skincare Tips 1. Wash face with cleanser. Washing your face with a cleanser really works well. You can use a hydrating cleanser, not something that strips all the moisture off but gives a good cleaning effect. It is especially important to wash your face before sleeping because the whole day’s dirt and bacteria are on your skin. People apply sunscreen, moisturizer, make-up and other skincare products on a daily basis. If you don’t wash all this off, it will stay on your skin and clog the pours. 2. Use an exfoliator. Since humidity attracts a lot of dirt, an exfoliator helps in further cleansing. In this weather, the pores start showing due to increase in sebum. So, using exfoliators, scrubs and masks two to three times a week work well on the skin. Image for representational purposes only (Photo Courtesy: iStock) 3. Apply light moisturizer. Don’t use a thick moisturizer. It can clog your skin during the rainy reason. Use lighter moisturizers or lotions that have less oil and hydration properties. 4. Manage use of actives. Avoid including a lot of actives like hyaluronic acid, glycolic acid, retinol, etc. People don’t use one skincare product. They use three to four, and they have different actives. For example, combinations of several different actives like vitamin E, vitamin C and retinol can completely destroy the skin barrier. People just find products on the internet and start using them without knowing their properties and effects on specific skin types. This should be avoided. Skin naturally has bacteria, which act as a barrier and protect the skin. People who have a weak skin barrier can make it worse by using actives. Nutrition is Key While most people associate skincare to applying something on the skin, its scope extends far beyond that. “Your skin is just 20 per cent of what you apply and 80 per cent of what you wat,” Dr. Bakshi states. Gut health greatly influences the skin, hence diet plays a key role in skincare. Nutrition Tips for Monsoon Skincare 1. Avoid street food. Humidity is the best environment for harmful bacteria to thrive. The same street food doesn’t trouble us a lot in summers because the high temperature kills the bacteria. So, eat home food as much as you can. If you crave dishes like samosa and pakoras, minimise its impact by cooking at home. 2. Consume local and seasonal fruits. Peach, apricot, pear, jamun, apple, papaya are all available in monsoon and most of them have antioxidant properties. Cherries are also great for the skin. If you don’t wish to eat them raw, you can use them to prepare innovative dishes like peach iced tea. 3. Have detox water. A detox drink can be prepared by infusing water with antioxidant-rich fruits and vegetables. For example, cut a cucumber in thin long slices and add it in water along with a lemon slice. This turns the water alkaline, which is good for the skin. Image for representational purposes only (Photo Courtesy: iStock) These simple yet effective steps are important to maintain healthy skin during the monsoon. While what you apply on the skin makes a difference, what you eat is equally significant. A balanced approach between the two will lead to rejuvenated and glowing skin. Also Read: MIDDAY EXPLAINS: Why is nutrition important during the monsoon season? Mumbai nutritionists tell you how to boost immunity

16 July,2024 07:27 PM IST | Mumbai | Raaina Jain
A pre-monsoon shower lashes Fort on June 13. Pic/Sameer Markande

Mid-Day Premium Monsoon illnesses: Vaccines and diet tips for women to combat lupus, arthritis

As monsoons intensify in the Indian subcontinent, medical experts warn that women are at a heightened risk of developing autoimmune diseases. The rise has been linked to increased humidity, moisture and a decrease in atmospheric pressure in the air that develops around this time of the year.  Shedding light on the various autoimmune diseases, Dr Pratima Thamke, a consultant obstetrician and gynaecologist working with Motherhood Hospital, Mumbai informs that, “Women are more likely to develop diseases like rheumatoid arthritis, multiple sclerosis, scleroderma, psoriatic arthritis, lupus and thyroid disease during the monsoon season.” Autoimmune diseases develop when one’s body tissues are attacked by the immune system. Studies (mention which ones) show that this condition affects approximately 8 per cent of people worldwide, of which 78 per cent are women. But why specifically women, we ask? In response, Dr Rajeev Gupta, director of internal medicine at the CK Birla Hospital, Delhi shares that, “Women experience significant hormonal fluctuations throughout their lives, particularly during puberty, pregnancy and menopause. These changes, especially in oestrogen levels, influence the immune system and make women more susceptible to mistakenly attacking their healthy tissues (autoimmunity).” With a focus on women's higher risk for autoimmune diseases, health experts provide insights into common conditions, their symptoms and how to address them.  Common autoimmune diseases that women are prone to: Rheumatoid Arthritis (RA)Marked by persistent joint pain, swelling and stiffness, particularly in the hands, wrists and knees, this condition is triggered by an immune system attack on the synovium, the lining of the membranes surrounding the joints, often influenced by genetic and environmental factors.  Systemic Lupus Erythematosus (SLE)Symptoms of this condition include fatigue, joint pain, skin rashes and fever. It also affects organs like the kidneys and heart. Causes include an attack on healthy tissues by the immune system, influenced by genetic predisposition, hormonal changes and environmental triggers like sunlight.  Hashimoto's ThyroiditisThis condition exhibits symptoms like fatigue, weight gain, sensitivity to cold and depression due to an underactive thyroid. When the immune system attacks the thyroid gland, it leads to hypothyroidism; exacerbating this disease.  Multiple Sclerosis (MS)Signs of this disease include numbness, weakness, balance issues and vision problems due to nerve damage. This is usually triggered when the immune system attacks the myelin sheath protecting nerve fibers, possibly causes by genetic susceptibility and environmental factors like viral infections.  PsoriasisA very common condition marked by red, scaly skin patches that can be itchy or painful, often on the elbows, knee and scalp. It is activated when Immune system dysfunction causes rapid skin cell production.  Graves' diseaseSymptoms of this condition include weight loss, rapid heartbeat, irritability and bulging eyes due to an overactive thyroid. What causes this is when the immune system produces antibodies that stimulate the thyroid gland to produce excessive hormones.  Sjogren's syndromeMarked by dry eyes and mouth, joint pain and fatigue, often associated with other autoimmune diseases like RA. Under this condition, the immune system attacks glands that produce moisture.  Also read: Respiratory Infections, swine flu, dengue, malaria on the rise as monsoon begins Vaccine to prevent autoimmune diseases During the monsoon season, high humidity and stagnant water enhance the chances of acquiring infections. It's crucial to consider vaccinations that help prevent common monsoon-related illnesses. Here are some vaccines recommended by  Dr Puneet Mashru, who works as a consultant-rheumatologist with Sir H N Reliance Foundation Hospital:  Influenza vaccineThe flu can be more severe for individuals with autoimmune diseases. Annual flu shots are recommended to protect against seasonal influenza. Pneumococcal vaccinePneumonia is a significant risk during the monsoon. The pneumococcal vaccine helps prevent infections caused by the bacteria Streptococcus pneumoniae. Hepatitis A and B vaccines:Hepatitis A and B can be contracted through contaminated water or food, which is more common during the monsoon. Vaccination helps protect against these viral infections. Typhoid vaccine:Typhoid fever is a risk due to waterborne bacteria. Typhoid vaccines are recommended, especially in areas where typhoid is prevalent. Cholera vaccine:In areas prone to cholera outbreaks, this vaccine can help prevent infection caused by contaminated water. Dietary tips to heal from autoimmune diseases Foods to eat: Herbs like garlic, ashwagandha, nettle, reishi mushrooms have anti-inflammatory propertiesOther anti-inflammatory foods include leafy greens, colourful fruits, ginger, turmeric, nuts, chia seedsFruits and vegetables rich in essential vitamins and minerals Whole grains, oats, fruits and vegetables are rich in fibreLean proteins: chicken, greek yoghurt, fish, legumes, beans, lentils Additional Tips:Stick to natural sugars found in fruits and avoid products with added sugars.Your gut thrives on a diet rich in vegetables and fruits.Complement your diet with protein and non-refined oils like those from nuts, seeds, avocados and olive oil.Foods like sauerkraut, kimchi, kombucha and yoghurt (if dairy-tolerant) support gut health.Eliminate foods that cause adverse reactions, such as gluten or dairy, based on lab tests if necessary. Why do autoimmune diseases aggravate during monsoons? Thamke informs that the increased humidity creates a conducive environment for the spread of bacteria, viruses and fungi, which are known to trigger autoimmune responses. Furthermore, for individuals with autoimmune diseases, getting infected with these microorganisms can lead to heightened immune activity and subsequent flare-ups.  The body's immune system, already prone to misidentifying and attacking its tissues, can become further dysregulated when dealing with external pathogens. This heightened state of immune activity can result in worsening symptoms of autoimmune diseases such as rheumatoid arthritis, lupus and psoriasis.  Additionally, the drop in atmospheric pressure during the monsoon season can influence the body's physiological processes. Lower pressure can lead to joint swelling and increased pain, which is particularly problematic for individuals with autoimmune conditions affecting the joints, like rheumatoid arthritis.  Also, during monsoons often there is lack of sunlight leading to vitamin D deficiency. Vitamin D deficiency is potentially linked with various autoimmune diseases, she adds.  When someone with autoimmune disease experiences flare-ups they may spot symptoms like their joints becoming stiff and swollen, feeling unusually tired, low level of energy, skin rashes and redness, and digestive issues like diarrhea, stomach pain and nausea. To manage these symptoms, one should choose clothing fabrics that provide warmth to protect their joints from cold weather during the monsoon season. To effectively combat these symptoms it becomes essential to maintain hygiene, eat well-balanced foods with essential nutrients, and reduce stress. Do not neglect these symptoms and immediately consult the doctor for expert guidance and tailored treatment.  Treatments to tackle autoimmune diseasesGupta shares that treatments for autoimmune diseases are multifaceted, aiming to manage symptoms, control the immune response and improve the quality of life for patients. Commonly, medications form the backbone of treatment strategies. Nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids are frequently prescribed to reduce inflammation and reduce pain. Disease-modifying antirheumatic drugs (DMARDs) are used to slow the progression of diseases like rheumatoid arthritis and lupus. Biologic agents target specific components of the immune system and are particularly effective in cases where traditional medications fail. These drugs include tumour necrosis factor (TNF) inhibitors and interleukin inhibitors, which have revolutionised treatment outcomes for many autoimmune conditions. In addition to pharmacological treatments, lifestyle modifications and supportive therapies play a crucial role in managing autoimmune diseases. Regular exercise and a balanced diet can help reduce inflammation and improve overall health. Physical therapy is often recommended to maintain joint flexibility and strength, especially for conditions like multiple sclerosis and rheumatoid arthritis. In some cases, patients may benefit from alternative therapies like acupuncture and dietary supplements, although these should be approached with caution and under medical supervision. Ensuring sufficient sunlight and vitamin D during monsoonsThamke recommends spending more time outdoors, especially in the morning when the sun is not too harsh, which can ensure sufficient vitamin D. During monsoon, it becomes a rare sight to spot sunlight due to gloomy temperatures. You can increase your vitamin D intake by eating foods that are rich in vitamins for effective results. This includes vitamin-rich foods like mushrooms, green leafy vegetables, cheese and dairy products like milk, yoghurt and cheese.  Disclaimer: This information does not replace professional medical advice. Consult a qualified specialist or your physician for personalised guidance.  

16 July,2024 03:31 PM IST | Mumbai | Ainie Rizvi
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Four new human cases of bird flu found in Colorado, US

Four new human cases of highly pathogenic avian influenza, or bird flu, infection in the state of Colorado have been confirmed by the US Centers for Disease Control and Prevention (CDC), bringing the total cases to nine since 2022. The four presumptive-positive cases were reported by the state on Friday, and the CDC confirmed the infection on Sunday, according to a press release, Xinhua news agency reported. All new cases were in farm workers who were involved in the depopulation of poultry at a commercial egg facility experiencing an outbreak of highly pathogenic avian influenza H5N1 virus. These workers reported symptoms after being exposed to infected poultry. The CDC said they reported "mild illness," including conjunctivitis and eye tearing, as well as fever, chills, coughing, sore throat and runny nose. These are the first cases of bird flu infection in poultry workers since 2022 when the first-ever US case of H5 in a poultry worker was reported in Colorado, said the CDC. A CDC team is on the ground in Colorado, supporting the assessment of the poultry outbreak and associated human cases, said the CDC, adding that "these cases again underscore the risk of exposure to infected animals." Bird flu outbreaks have affected poultry in 48 US states and 152 dairy herds in 12 states as of July 12, according to the CDC. Also Read: Naegleria fowleri: What is this brain-eating amoeba threatening Kerala and its potential risks in Mumbai This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/ reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

16 July,2024 01:32 PM IST | Los Angeles | IANS
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Child vaccinations stalled after COVID pandemic, WHO and UNICEF call for action

Two UN agencies have called for a catch-up in child immunisation, warning global vaccinations of children stalled last year, leaving 2.7 million unvaccinated or with insufficient inoculations. The latest World Health Organization (WHO) and the UN Children's Fund (UNICEF) estimates of national immunisation coverage provide the world's largest and most comprehensive dataset on immunisation trends for vaccinations against 14 diseases. The estimates "underscore the need for ongoing catch-up, recovery and system-strengthening efforts", Xinhua news agency reported. They said on Monday that childhood immunisation levels stalled in 2023, compared to pre-pandemic levels in 2019, leaving many without life-saving protection, notably from measles. New data reveals that nearly three in four infants live in countries where low vaccine coverage is driving measles outbreaks. "The latest trends demonstrate that many countries continue to miss far too many children," said UNICEF Executive Director Catherine Russell. "Closing the immunisation gap requires a global effort, with governments, partners, and local leaders investing in primary healthcare and community workers to ensure every child gets vaccinated and that overall healthcare is strengthened." The agencies' data shows the number of children who received three doses of the vaccine against diphtheria, tetanus and pertussis (DTP) in 2023 -- a key marker for global immunisation coverage -- stalled at 84 per cent (108 million). However, the number of children who did not receive a single dose of the vaccine increased from 13.9 million in 2022 to 14.5 million in 2023. "More than half of unvaccinated children live in the 31 countries with fragile, conflict-affected and vulnerable settings, where children are especially vulnerable to preventable diseases because of disruptions and lack of access to security, nutrition, and health services," they said. "Additionally, 6.5 million children did not complete their third dose of the DTP vaccine, which is necessary to achieve disease protection in infancy and early childhood." Also Read: Feeling stressed? Here’s how you can regulate the stress hormone cortisol This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/ reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

16 July,2024 12:28 PM IST | New Delhi | IANS
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Yoga can help manage pain in Rheumatoid Arthritis patients: AIIMS study

For people suffering from Rheumatoid Arthritis (RA), yoga may not only manage symptoms like pain and stiffness but could also contribute to disease control and improved quality of life, a study by AIIMS-New Delhi said on Monday. The collaborative study by the Lab for Molecular Reproduction and Genetics, Anatomy Dept, and Department of Rheumatology AIIMS-New Delhi, supported by the Department of Science and Technology (DST), explored the effects of yoga at a cellular and molecular level in RA patients and how yoga may benefit RA patients beyond just pain relief. RA is a chronic autoimmune disease that causes inflammation in the joints. It causes joint damage and pain and can affect other organ system as well like the lungs, heart and brain.  The study by Dr Rima Dada and her team, published in Scientific Reports, documented reduced pain perception, improved joint mobility, decreased disability, and enhanced overall quality of life for patients performing yoga.  These benefits were attributed to yoga's ability to establish immunological tolerance and molecular remission. The findings showed that yoga may help manage stress, a known trigger for RA symptoms.  “By lowering stress hormones like cortisol, yoga may indirectly reduce inflammation, may improve mitochondrial function, which can impact energy production and cellular health and reduce the severity of comorbid depression,” the team noted. The research provides evidence for the potential of yoga as a complementary therapy for RA patients. This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/ reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever.

16 July,2024 11:42 AM IST | New Delhi | IANS
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Mid-Day Premium What makes Papaya a superfood?

Agree with this writer or not, most people find papayas to be a boring. Beyond the sweetness, the very texture of the bright yellow-greenish fruit may often put people off. This can often lead to it lying on the fruit cart longer than other fruits. However, there is a lot more to the fruit than most people know as papayas have many health benefits especially during the monsoon season, according to Mumbai dieticians, and if you have been hesitant till now, then Mumbai chefs say you can even innovate with them in different ways to suit your palate. Every monsoon season, Mumbai doctors advise Mumbaikars to be careful and take care of their health. They not only stress on consuming healthy meals and a balanced diet but also emphasise on consuming seasonal produce. While there are many different kinds of monsoon vegetables and fruits, papayas are barely highlighted in our diets unless due to the intervention of a health expert.Dr Monal Velangi, senior dietitian, K J Somaiya Medical College, Hospital and Research Centre in Sion explains, “Papayas are rich in vitamin C, which helps boost the immune system and fight off common infections that are more prevalent in the rainy season. The enzyme papain in papayas aids digestion, making them beneficial for preventing issues like bloating, constipation, and diarrhoea that can occur more frequently during the monsoons.”With the monsoon here and need for nutrition, spoke to Sir HN Reliance Foundation Hospital in Girgaon and Velangi. They not only stress on the health benefits of eating the fruit but also tell you why it makes a delicious addition to their diet. Beyond the advice of the health experts, they also share easy recipes to follow and use papaya in your food this season, but not without Mumbai chefs sharing some delicious recipes to elevate the fruit like you have never eaten it before. What are the health benefits of eating papaya during the monsoon?Premani: Papaya is rich in antioxidants like vitamin C and beta carotene which help to strengthen immune system, and hence fight infections during monsoons. It is rich in papain which aids in digestion and helps relieve indigestion and bloating as well.   Velangi: Papaya is a highly nutritious fruit that offers numerous health benefits, especially during the monsoon season. Firstly, papayas are rich in vitamin C, which is essential for boosting the immune system and helping the body fight off common infections such as dengue that are more prevalent during the rainy season. The high-water content in papayas also helps with hydration, which is crucial in the humid monsoon weather. Papayas contain an enzyme called papain that aids digestion, making them beneficial for preventing digestive issues like bloating, constipation, and diarrhoea that can occur more frequently during the monsoons. Additionally, papayas have antimicrobial and antifungal properties. The antioxidants and anti-inflammatory compounds in papayas also promote skin health and can protect against monsoon-related skin problems. Incorporating papayas into diet during the monsoon season can provide a range of health benefits and keep feeling healthy throughout the rainy months. What are the nutritional benefits of eating papayas during monsoon? Do they differ from other times of the years?Premani: The fibre in the papaya helps to relieve constipation and improves gut health as well. It can help to regulate the gut microbiome, thereby preventing dysbiosis and improving the immune system. There are studies that show that papaya has an anti-fungal effect on the body and hence can help fight of fungal infections which are very common in the monsoon season.   Velangi: Eating papayas during the monsoon season provides several nutritional benefits that are particularly valuable during this time of year. Papayas are rich in vitamin C, which helps boost the immune system and fight off common infections that are more prevalent in the rainy season. The enzyme papain in papayas aids digestion, making them beneficial for preventing issues like bloating, constipation, and diarrhoea that can occur more frequently during the monsoons. Papayas also have antimicrobial and antifungal properties that can help prevent bacterial and fungal infections, which are more common in the humid monsoon weather. Additionally, the high-water content in papayas helps with hydration, which is crucial during the monsoon season. While the overall nutritional value of papayas remains consistent throughout the year, their benefits become especially important during the monsoons when certain health issues are more likely to arise. What makes papayas a unique addition to the diet apart from other fruits during the monsoon?Premani: Papaya is known to be an anti-fungal and anti-bacterial in nature which helps to fight off the potential infections that can occur during monsoons.  Velangi: Papayas stand out among other fruits during the monsoon season due to their unique combination of nutritional properties that address common health concerns prevalent during this time of year. The unique combination of digestive enzymes, antimicrobial properties, immune-boosting nutrients, and hydrating qualities make papayas a particularly valuable addition to the diet during the monsoon season, when certain health issues are more likely to arise. These benefits set papayas apart from other fruits during this time of year. Apart from that, the juicy, moisturising and soft texture makes it easy to eat for even babies and elderly. The bright orange colour of papaya also makes it appealing as a solo dish or for garnish. How can papayas be included in people’s diet in terms of different types of dishes? Please help with easy dish recipes.Premani: Papayas can be included as smoothies, salads, chutney, or even cooked in savoury dishes. Some recipes can be papaya pachadi or papaya curry, raw papaya salad, papaya salsa, papaya with granola and yogurt, can also be included in the form of jam, marmalade, or even as or in ice cream.   Velangi: People can include papayas in the form of raw as well as processed form. Raw papaya pieces can go as a solo fruit dish or in fruit salads or in vegetable salads or meat salads. Plain papaya fruit juice or mix fruit juice can be made. It can also be incorporated in soups. It can be helpful in making papaya milkshakes. Another great options would be smoothies. The papaya purees can help in soft diets for babies and elderly. Papaya can be used in making doughs, healthy cakes. Papayas can be made into hot delicious traditional papaya halwa or continental papaya salsa-based dishes. What are the common misconceptions about eating papayas?Premani: According to Ayurveda, papaya is considered as a ‘heaty’ food and hence there is a misconception that it can create heat in the body and cause harm. It is also believed that the seeds are inedible and should be removed before consumption. However, they have potential health benefits and can be consumed in moderation. Velangi: These are some of the common misconceptions about papayas:  1. Myth: Papaya have low nutrient values. Truth: Papaya is a rich source of fiber, vitamin C, folate, and antioxidant (Koul et al 2022).  2. Myth: Pregnant women must avoid papaya.Truth: This is one of the common myths about the papaya. Unripe papaya is a source of latex that can be dangerous for women as it can induce early labour due to triggering uterine contraction consumption of papaya juice is associated with increases the haemoglobin in pregnant women with anemia (Wahyuntari etal., 2020). However, ripe papaya can be a healthy food option for the women and a source of carotenoids.How much papaya needs to be consumed per meal?Premani: Around 50-75 gm can be consumed per day once a day.  Velangi: There is no specific recommended amount of papaya to consume per meal. Individual needs may vary based on factors such as age, gender, activity level, and overall health status. 1 cup papaya (100g) has 43 calories and provides 68% of daily vitamin C and 32% of daily vitamin A. Per day 1 cup papaya is enough to get all the health benefits. Additionally, Mumbai’s chefs also share unique recipes that you can make beyond eating the fruit plain to innovating with them in different ways. Papaya ka MurabbaThere are so many different ways to eat papaya and masterchef Mohammed Shareef at ITC Grand Central in Parel, believes one of the easiest ways is to make a papaya murabba, especially during the monsoon. He explains, "During the monsoon, papaya murabba is a pleasant delicacy that satisfies the palate and improves health. It's perfect for eating throughout the rainy season because of its rich flavour and digestive qualities."Ingredients:Raw papaya 1 kgSugar 1 kgVinegar 700 mlRaisins 150 gmSaunf/Aniseed - 20 gmKalonji 10 gmSalt 5 gmWhole red chillies (remove seeds) 10 piecesMilk 30 mlNutmeg 1-3 gm Method:1. Wash and peel the skin of the papaya. Remove the seeds and then cut papaya into thin slices.2. Heat the milk in a kadai (wok) and add sugar and vinegar and mix well.3. Add the papaya and all the spices and raisins and cook well for 20-30 minutes until the consistency becomes sticky.4. Add nutmeg by grating it and mix well.5. Let is set and cool for 1 hour and then transfer into a jar.6. Serve it as a compliment. Papaya, Prosciutto & Arugula SaladAt Estella, Mumbai chef Rahul Punjabi says you can make a refreshing dish with the Papaya, Prosciutto & Arugula Salad, which features as a starter on their a la carte menu. He explains, “Prosciutto and melons are a classic Italian combination. The salty salumi is offset nicely by the sweet freshness of the melons. With papayas bright and fresh in season right now, they are a great substitute for melons to add balance to our cold cuts. Paired with lashings of aged aceto balsamico and some freshly shaved parmesan cheese. The papaya features in two forms, as fresh balls of papaya, and also coated with sugar and caramelised with a blow torch. A little arugula salad adds some form of body and herbaceous spice.” For the dressing, you will need:Valencia orange zest 1 noValencia orange juice 60 ml White wine vinegar 40 mlWhole grain mustard 1 tspDijon mustard 1 tbsp   Honey 2 tbspSesame oil 10 mlExtra Virgin Olive Oil 100 mlSalt 1 gmMethod: For the Papaya: 1. Choose the ripest papaya and peel the skin. Using a melon scooper, make little balls with the papaya. Reserve on a micro-perforated cloth. 2. Keep 100 gm of the papaya balls aside and with the remaining 100 gm half, dust them with some icing sugar and toast them with a blowtorch. This step is purely optional if you have the tools on hand, if not, simply allow them to soak in the icing sugar and 'macerate'. 3. Add the orange zest into a bowl and juice the orange directly into the bowl through a strainer to avoid any pips. Add your mustards, vinegars, honey and salt. 4. Give it a brief whisk and then slowly pour in your sesame oil and extra virgin olive oil while continuing to whisk. Your dressing will be emulsified briefly so give it a whisk once more before coating your leaves. Set aside in the fridge. For the nut mix: Almonds 30 gm Pistachios 10 gmPecan nuts 10 gm Method:1. Toast the almonds, pistachios and pecan nuts separately in the oven. 2. Once cool, chop them roughly with a knife and reserve.  To assemble, you will need: Baby arugula leaves 30 gmOrange honey dressing 3 tbspBocconcini cheese (halved) 3 pcsPapaya balls 200 gmProsciutto, thinly sliced 50 gmNut mix 15 gmBalsamic glazeEdible flowers for garnish Method: 1. Begin by coating the baby arugula leaves with the dressing, assemble them in your salad bowl in a wreath along the slope of the bowl. 2. Fill the centre gap with half of your papaya balls and then add your Prosciutto strips onto thearugula. Fill the gaps with your remaining papaya balls and bocconcini balls. 3. Garnish with a drizzle of the Balsamic glaze, the nuts mix on top and some petals of edible flowers.4. The dish can be made vegetarian by substituting the prosciutto for some more bocconcini, just ensure to season the bocconcini with some salt and pepper if not using prosciutto. Pomelo and Papaya SaladIf you want to make the best of the season, then chef Phankri Bey, brand chef of VietNom, says you can Pomelo and Papaya Salad. He explains, "It is rich in vitamins, minerals, and antioxidants. During the monsoon season, when temperatures drop and hygiene becomes a concern, these fruits are excellent for boosting immunity and fighting infections common in this period. Their high-water content helps keep people hydrated in humid conditions. Additionally, they add variety to the diet and contribute to a balanced and nutritious meal." Ingredients:Pomelo 70 gm Raw papaya 120 gmRoasted peanut 15gmFried garlic 10 gmFried onion 10 gmMint 5 gmCoriander 5 gmBasil 5 gmRaw mango 10 gmCoconut sweet chilly dressing 60 gmCaramelised onion 10 gm Method:1. Take whole papaya and peel. After peeling with the help of julienne peeler peel the papaya. Rinse the papaya with water and soak in chilled ice water for 15-30 minutes.2. Once soaked rinse them and keep in a container in chillies. 3. Peel pomelo and keep the segments aside. 4. Take a bowl add the shredded pomelo and papaya then add all the ingredients (with herbs and burnt garlic, onion, peanuts) along with coconut sweet chilly dressing (60 ml).5. Mix the salad well with dressing and serve chilled.6. Garnish with micro green and edible flower (optional). For coconut sweet chilli base dressing:Mango pulp 1,700 gm Sweet chilli sauce 980 gm Fresh red chilli chop – 20 gmCoconut milk powder – 8 gmMint chop 5gms Coriander chop 5 gmBasil chop 5 gmJapanese mayo/veg mayo (optional) 200 gm  Method:1. Take a bowl and mix Japanese mayo veg mayo.2. Now add coconut milk powder and sweet chilli sauce with fine red chillies.3. In the end, add herbs.

16 July,2024 11:19 AM IST | Mumbai | Nascimento Pinto
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Chandipura virus: Six kids dead, cases rising in suspected outbreak in Gujarat

Gujarat health minister Rushikesh Patel on Monday announced that six children have died from suspected Chandipura virus infections in the past five days, while the number of cases has risen to 12.  "Of the 12 patients, four are from Sabarkantha district, three from Aravalli, and one each from Mahisagar and Kheda. Additionally, two patients from Rajasthan and one from Madhya Pradesh received treatment in Gujarat. Six deaths have been reported, but confirmation is pending based on sample results," Patel said. Most of the deaths occurred at the civil hospital in Himatnagar in Sabarkantha district. All 12 samples, including eight from Sabarkantha, have been sent to the National Institute of Virology (NIV), Pune for verification. The Minister assured the public that while there is no need for panic, caution is necessary. "Over 400 houses and 19,000 people have been screened for the virus. Chandipura is not a new virus. It mainly affects children aged 9 months to 14 years and is more prevalent in rural areas. Symptoms include fever, vomiting, diarrhoea, and headache. A doctor should be consulted if these symptoms are observed," he said, Patel said that in Gujarat, nine cases have been registered across four districts, with three cases involving individuals from other states residing in Gujarat. "Samples have been sent to Pune for confirmation, and results are awaited. Though six deaths have been reported, it is too soon to confirm if they were caused by the Chandipura virus," he added. The virus, a member of the Vesiculovirus genus in the Rhabdoviridae family, causes fever with flu-like symptoms and acute encephalitis. It is transmitted by vectors such as mosquitoes, ticks, and sandflies. The Chandipura virus, a member of the Rhabdoviridae family, leads to symptoms akin to flu and can cause acute encephalitis, a severe inflammation of the brain. It was first identified in 1965 in Maharashtra and has been linked to various outbreaks of encephalitic illness in the country. A significant outbreak occurred in 2003 in Andhra Pradesh and Maharashtra, resulting in 183 deaths among 329 affected children. Sporadic cases and fatalities were also noted in Gujarat in 2004. In the present situation, paediatricians at Himatnagar Civil Hospital suspected the virus after four children died on July 10 and subsequently sent their samples to NIV for confirmation. Four additional children later exhibited similar symptoms. This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/ reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever.

16 July,2024 11:19 AM IST | Gandhinagar | IANS
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Two liters of blood removed from a woman’s abdomen

Mumbai-based housewife Rabia Khan (name anynonymised at request) arrived at Lilavati casualty with difficulty in breathing and giddiness and abdominal pain. On arrival, her pulse was recorded at 130 b / min. BP was 80/60 mm. Upon abdominal examination, there was massive bruising of the anterior abdominal wall suggesting haemorrhage in the wall. Also, all signs of free fluid in the abdomen were positive. Her abdominal USG revealed more than 2 litres of free fluid in her abdomen and a right-sided ovarian mass almost 5cm by 6cm. Her blood investigation revealed a Hb of 5g/dl. Her INR was 10 and her PTT was not recordable. All the coagulation profiles were deranged. Basically, the patient was in DIC and hemorrhagic shock. Elaborating on her case, Dr Rekha Agrawal, senior honorary consultant in obstetrics and gynaecology, Lilavati Hospital, Bandra, Mumbai informs how the patient had experienced massive intra-abdominal bleeding. “Khan had undergone an aortic valve replacement surgery 4 years ago where she was recommended an anticoagulant medication regimen. The patient however failed to monitor her INR (international normalised ratio) regularly which resulted in her condition.” Also read: Monsoon illnesses: Vaccines and diet tips for women to combat lupus, arthritis With the help of haematologist Dr Abhay Bhave and intensivist Dr Srinivasan, packed cells factor Nova 7 and FFP were transfused. The patient was admitted at 11 pm she was even bleeding from an arterial puncture. Her entire abdomen was bruised with signs of intra-abdominal bleeding. She was suffering from early disseminated intravascular coagulation (DIC), a rare and nearly fatal blood clotting disorder where the body consumes all clotting factors. Because of this consumption, coagulopathy blood does not clot if not treated in time, patient can bleed from all mucous membranes.   When one gets hurt, the clotting factors play a crucial role in stopping the bleeding. These clotting factors are consumed rapidly if there is bleeding inside the body. There was internal bleeding in her abdomen, causing all the clotting factors to be fully utilised. Her blood had become so thin that any test or procedure could result in bleeding from the puncture site of her body, adds Agarwal. She continues, “The goal was to normalise her INR so that we could do laparoscopic surgery and stem the bleeding. However, it was a race against time. In the next 1/2 hours, the patient's haemoglobin plunged to 4.5. She received 8-10 fresh frozen plasma, packed blood cells. platelet infusions and Nova 7 over six hours. This brought her blood levels to a safe range for surgery.” Under the expert anaesthetic team of Lilavati, Agarwal performed laparoscopic surgery (keyhole surgery,) which minimises the time of surgery and the morbidity accompanied by open surgery. During the laparoscopic surgery, it was discovered that she was bleeding from a haemorrhagic ovarian cyst, which had caused 2 liters of blood to accumulate in her abdomen. The bleeding ovary and fallopian tube were excised, and the abdomen was cleared of all free blood. A total of 2.2 liters of blood was successfully removed, effectively stopping the bleeding. Her clotting profile returned to normal. Within the next 48 hours, she made a full recovery and is now ready for discharge. Upon discharge, the patient has been advised to carefully monitor her INR and follow up closely with her cardiologist. Her hemoglobin level at discharge was 8 g/dL, and she has been given an IV infusion of 1000 mg of Ferric Carboxymaltose to replenish her iron stores. “As I heard the words intra-abdominal bleeding, I panicked. However, the team of doctors worked tirelessly to stabilise me and assist me in fighting against the odds,” concluded Khan. Also read: Thane road ‘disappears’ weeks after being repaired

16 July,2024 11:18 AM IST | Mumbai | mid-day online correspondent
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